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产品信息
PA5-82964
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human WDR77. Recombinant protein control fragment (Product #RP-94077).
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Anitgen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2790120
产品详细信息
Immunogen sequence: SEDCSIAVLD SSLSELFRSQ AHRDFVRDAT WSPLNHSLLT TVGWDHQVVH HVVPTEPLPA PGPASVTE
靶标信息
WDR77 is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ac2-269; Androgen receptor cofactor p44; MEP-50; Methylosome protein 50; Methylosome protein WDR77; MGC2722; OTTHUMP00000013473; p44/Mep50; RP11-552M11.3; testis tissue sperm-binding protein Li 44a; WD repeat-containing protein 77
基因别名: 2610003I18Rik; 2610312E17Rik; C79984; HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/MEP50; RGD1310479; WD45; WDR77
UniProt ID: (Human) Q9BQA1, (Mouse) Q99J09, (Rat) Q4QR85
Entrez Gene ID: (Human) 79084, (Mouse) 70465, (Rat) 310769
spliceosomal snRNP assembly
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
peptidyl-arginine N-methylation
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
negative regulation of epithelial cell proliferation involved in prostate gland development
negative regulation of cell proliferation
regulation of nucleic acid-templated transcription
