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XAB2 Antibody (PA5-100368) in ICC/IF
Immunofluorescent analysis of XAB2 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and XAB2 polyclonal antibody (Product # PA5-100368) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-100368
产品规格
种属反应
Human,
Mouse,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human XAB2(Accession Q9HCS7), corresponding to amino acid residues E447-L497.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2849881
产品详细信息
Antibody detects endogenous levels of total XAB2.
靶标信息
A novel protein designated XAB2 (XPA-binding protein 2) interacts with XPA, a factor central to both nucleotide excision repair subpathways. Data suggests that XAB2 is a novel component involved in transcription-coupled repair and transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: crn-related protein kim1; DKFZp762C1015; HCNP protein; Pre-mRNA-splicing factor SYF1; Protein HCNP; SYF1 homolog, RNA splicing factor; SYF1 pre-mRNA-splicing factor; XPA-binding protein 2
基因别名: 0610041O14Rik; AV025587; HCNP; HCRN; KIAA1177; NTC90; PP3898; SYF1; XAB2
UniProt ID: (Human) Q9HCS7, (Mouse) Q9DCD2
Entrez Gene ID: (Human) 56949, (Mouse) 67439
generation of catalytic spliceosome for first transesterification step
mRNA splicing, via spliceosome
blastocyst development
transcription-coupled nucleotide-excision repair
transcription, DNA-templated
cerebral cortex development
DNA repair
RNA processing
mRNA processing
cellular response to DNA damage stimulus
RNA splicing
