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产品信息
PA5-65352
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human XRCC6BP1. Recombinant protein control fragment (Product #RP-106038).
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2665291
产品详细信息
Immunogen sequence: EQLQQQHVSCQ VFPERLAQGN PQQGFFSSFF TCNQKCQLRL LKTLETNPYV KLLLDAMKHS GCAVNKDRHF
Highest antigen sequence identity to the following orthologs - mouse 68%, rat 69%.
靶标信息
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
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生物信息学
蛋白别名: Ku70 binding protein 3; Ku70-binding protein 3; Mitochondrial inner membrane protease ATP23 homolog; XRCC6 binding protein 1; XRCC6-binding protein 1
基因别名: ATP23; KUB3; XRCC6BP1
UniProt ID: (Human) Q9Y6H3
Entrez Gene ID: (Human) 91419
