Abnova

YWHAG Polyclonal Antibody, MaxPab™

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YWHAG Antibody (H00007532-D01P) in WB

Western Blot analysis of YWHAG expression in transfected 293T cell line by YWHAG MaxPab polyclonal antibody. Lane 1: YWHAG transfected lysate(28.30 KDa). Lane 2: Non-transfected lysate. .

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产品信息

H00007532-D01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

YWHAG (NP_036611.2, 1 a.a. approximately 247 a.a) full-length human protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5-1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MVDREQLVQK ARLAEQAERY DDMAAAMKNV TELNEPLSNE ERNLLSVAYK NVVGARRSSW RVISSIEQKT SADGNEKKIE MVRAYREKIE KELEAVCQDV LSLLDNYLIK NCSETQYESK VFYLKMKGDY YRYLAEVATG EKRATVVESS EKAYSEAHEI SKEHMQPTHP IRLGLALNYS VFYYEIQNAP EQACHLAKTA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDD DGGEGNN

靶标信息

14-3-3 gamma encodes a product that belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 14-3-3 gamma; 14-3-3 protein gamma; KCIP-1; Protein kinase C inhibitor protein 1; protein phosphatase 1, regulatory subunit 170; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide

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基因别名: 14-3-3GAMMA; PPP1R170; YWHAG

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UniProt ID: (Human) P61981

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Entrez Gene ID: (Human) 7532

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功能

protein kinase C binding insulin-like growth factor receptor binding protein binding protein kinase C inhibitor activity protein domain specific binding receptor tyrosine kinase binding poly(A) RNA binding scaffold/adaptor protein

参与通路

G2/M transition of mitotic cell cycle negative regulation of protein kinase activity protein targeting regulation of signal transduction cellular response to insulin stimulus regulation of neuron differentiation regulation of synaptic plasticity membrane organization negative regulation of protein serine/threonine kinase activity positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway