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YY1 Antibody (MA5-42708) in ICC/IF
Confocal imaging (Immunocytochemistry) of YY1 in HeLa cells. Samples were incubated with YY1 Monoclonal antibody (Product # MA5-42708) using a dilution of 1:50 (Red). The cells were counterstained with alpha Tubulin Mouse mAb (dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.
产品信息
MA5-42708
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6J6L1
抗原
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human YY1 (P25490).
偶联物
形式
Liquid
浓度
0.41 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2911849
产品详细信息
Positive test controls include: Mouse liver, Mouse kidney, Mouse spleen, Rat spleen, U-251MG, HeLa, Jurkat, Raji. The target is usually found in the following locations: Nucleus matrix.
Immunogen sequence: PGNKKWEQKQ VQIKTLEGEF SVTMWSSDEK KDIDHETVVE EQIIGENSPP DYSEYMTGKK LPPGGIPGID LSDPKQLAEF ARMKPRKIKE DDAPRTIACP H
靶标信息
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Delta transcription factor; INO80 complex subunit S; NF-E1; Transcriptional repressor protein YY1; UCR-motif DNA-binding protein; UCRBP transcription factor; Yin and yang 1; Yin and Yang 1 protein; Yin Yang 1; YY-1
基因别名: AW488674; DELTA; INO80S; NF-E1; NMP-1; NMP1; UCRBP; YIN-YANG-1; YY1
UniProt ID: (Human) P25490, (Mouse) Q00899
Entrez Gene ID: (Human) 7528, (Rat) 24919, (Mouse) 22632
four-way junction DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
enhancer sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
transcription corepressor activity
RNA binding
protein binding
zinc ion binding
transcription regulatory region DNA binding
SMAD binding
histone deacetylase binding
sequence-specific DNA binding
metal ion binding
nucleic acid binding
C2H2 zinc finger transcription factor
negative regulation of transcription from RNA polymerase II promoter
double-strand break repair via homologous recombination
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
spermatogenesis
response to UV-C
negative regulation of gene expression
cell differentiation
cellular response to UV
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
RNA localization
anterior/posterior pattern specification
positive regulation of gene expression
response to prostaglandin F
positive regulation of transcription from RNA polymerase II promoter
camera-type eye morphogenesis
chromosome organization
cellular response to interleukin-1
DNA repair
DNA recombination
