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Immunogen sequence: SFDSGVSSS IGTEPDSVEQ QFGPGAARDS QAEPTQPEQA AEAPAEGGPQ TNQLETGASS PERSNEVEMD STVITVSNSS DKSVLQQPSV NTSIGQPLPS TQLYLRQTET LTSNLRMPLT LTSNTQVIGT AGNTYLPALF TTQPAGSGPK PFLFSLPQPL AGQQTQFVTV FQPGLSTFTA QLPAPQPLAS SAGHSTASGQ GEKKPYECTL CNKTFTAKQN YVKHMFVHTG EKPHQCSICW RSFSLKDYLI KHMVTHTGVR AYQCSICNKR FTQKSSLNVH MRLHRGEKSY ECYICKKKFS HKTLLERHVA LHSASNGTPP AGTPPGARAG PPGVVACTEG TTYVCSVCPA KFDQIEQFND HMRMHVSDG (301-668 aa encoded by BC029041)
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BTB/POZ domain zinc finger factor HOF; BTB/POZ zinc finger protein DPZF; dendritic cell-derived BTB/POZ zinc finger; Dendritic-derived BTB/POZ zinc finger protein; POZ/zinc finger transcription factor ODA-8; Zinc finger and BTB domain-containing protein 20; Zinc finger protein 288
基因别名: 1300017A20Rik; 7330412A13Rik; A930017C21Rik; D16Wsu73e; DPZF; HOF; ODA-8S; Oda8; PRIMS; ZBTB20; Zfp288; ZNF288
UniProt ID: (Human) Q9HC78, (Mouse) Q8K0L9
Entrez Gene ID: (Human) 26137, (Mouse) 56490