Proteintech

ZBTB7B Polyclonal Antibody

ZBTB7B Antibody in Immunocytochemistry (ICC/IF)

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ZBTB7B Antibody (11341-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using ZBTB7B antibody 11341-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

ZBTB7B Antibody in Immunoprecipitation (IP)

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产品信息

11341-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:4,000

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免疫组化 (IHC)

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免疫细胞化学 (ICC/IF)

1:10-1:100

免疫沉淀 (IP)

0.5-4.0 µg

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Not Applicable

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

ZBTB7B Fusion Protein Ag1888 (1-300 aa encoded by BC012070)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.37 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MGSPEDDLI GIPFPDHSSE LLSCLNEQRQ LGHLCDLTIR TQGLEYRTHR AVLAACSHYF KKLFTEGGGG AVMGAGGSGT ATGGAGAGVC ELDFVGPEAL GALLEFAYTA TLTTSSANMP AVLQAARLLE IPCVIAACME ILQGSGLEAP SPDEDDCERA RQYLEAFATA TASGVPNGED SPPQVPLPPP PPPPPRPVAR RSRKPRKAFL QTKGARANHL VPEVPTVPAH PLTYEEEEVA GRVGSSGGSG PGDSYSPPTG TASPPEGPQS YEPYEGEEEE EELVYPPAYG LAQGGGPPLS P (1-300 aa encoded by BC012070)

靶标信息

ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g., COL1A1; MIM 120150) and has a role in development.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

LAP2β transmits force to upregulate genes via chromatin domain stretching but not compression.

Acta biomaterialia

Sun J,Chen J,Amar K,Wu Y,Jiang M,Wang N

Thu Jun 01 00:00:00 EDT 2023

Epigenetic DNA methylation of Zbtb7b regulates the population of double-positive CD4⁺CD8⁺ T cells in ulcerative colitis.

Journal of translational medicine

Xu HM,Xu J,Yang MF,Liang YJ,Peng QZ,Zhang Y,Tian CM,Nie YQ,Wang LS,Yao J,Li DF

Mon Jun 27 00:00:00 EDT 2022

Epigenetic DNA methylation of Zbtb7b regulates the population of double-positive CD4⁺CD8⁺ T cells in ulcerative colitis.

Journal of translational medicine

Xu HM,Xu J,Yang MF,Liang YJ,Peng QZ,Zhang Y,Tian CM,Nie YQ,Wang LS,Yao J,Li DF

Mon Jun 27 00:00:00 EDT 2022

生物信息学

蛋白别名: c-Krox; DKFZp686G01254; hcKrox; Krueppel-related zinc finger protein cKrox; RP11-307C12.9; T helper-inducing POZ/Krueppel factor; T-helper-inducing POZ/Krueppel-like factor; Vzinc finger and BTB domain containing 7B; Zfp-67; zinc finger and BTB domain containing 15; Zinc finger and BTB domain-containing protein 15; Zinc finger and BTB domain-containing protein 7B; Zinc finger protein 67; Zinc finger protein 67 homolog; Zinc finger protein 857B; Zinc finger protein Th-POK

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基因别名: c-KROX; CKROX; hcKROX; THPOK; ZBTB15; ZBTB7B; ZFP-67; ZFP67; ZNF857B

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UniProt ID: (Human) O15156, (Mouse) Q64321

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Entrez Gene ID: (Human) 51043, (Rat) 295248, (Mouse) 22724

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功能

DNA binding protein binding metal ion binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding nucleic acid binding transcription factor activity, sequence-specific DNA binding protein homodimerization activity

参与通路

transcription from RNA polymerase II promoter positive regulation of gene expression regulation of CD4-positive, alpha-beta T cell differentiation regulation of CD8-positive, alpha-beta T cell differentiation positive regulation of transcription from RNA polymerase II promoter regulation of transcription, DNA-templated multicellular organism development ectoderm development cell differentiation transcription, DNA-templated