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Immunogen sequence: CNCIDLSKSP DPDKSTGTDC RSNLETESSH QSVCTDTSAT SCNCKATEDA SDLNDDDNLP TQELYYVFDK FILTSGK
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 75%.
WDR77 is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: PAP associated domain containing 3; RP23-406B13.1; Terminal uridylyltransferase 4; TUTase 4; Zinc finger CCHC domain-containing protein 11; zinc finger, CCHC domain containing 11
基因别名: KIAA0191; PAPD3; TUT4; ZCCHC11
UniProt ID: (Human) Q5TAX3
Entrez Gene ID: (Human) 23318
分子生物学功能: nucleotidyltransferase transferase metabolite interconversion enzyme