Proteintech

ZCCHC8 Polyclonal Antibody

ZCCHC8 Antibody in Immunocytochemistry (ICC/IF)

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ZCCHC8 Antibody (23374-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HepG2 cells using 23374-1-AP (ZCCHC8 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

ZCCHC8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

23374-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

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免疫组化（石蜡） (IHC (P))

1:50-1:500

免疫细胞化学 (ICC/IF)

1:50-1:500

免疫沉淀 (IP)

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产品规格

种属反应

Human, Mouse

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

ZCCHC8 Fusion Protein Ag19985 (355-707 aa encoded by BC065918)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.25 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: KSVTYDLSK LVNYPGFNIS TPRGIPDEWR IFGSIPMQAC QQKDVFANYL TSNFQAPGVK SGNKRSSSHS SPGSPKKQKN ESNSAGSPAD MELDSDMEVP HGSQSSESFQ FQPPLPPDTP PLPRGTPPPV FTPPLPKGTP PLTPSDSPQT RTASGAVDED ALTLEELEEQ QRRIWAALEQ AESVNSDSDV PVDTPLTGNS VASSPCPNEL DLPVPEGKTS EKQTLDEPEV PEIFTKKSEA GHASSPDSEV TSLCQKEKAE LAPVNTEGAL LDNGSVVPNC DISNGGSQKL FPADTSPSTA TKIHSPIPDM SKFATGITPF EFENMAESTG MYLRIRSLLK NSPRNQQKNK KASE (355-707 aa encoded by B C065918)

靶标信息

ZCCHC8 may be involved in pre-mRNA splicing.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2.

Nucleic acids research

Hou L,Wei Y,Lin Y,Wang X,Lai Y,Yin M,Chen Y,Guo X,Wu S,Zhu Y,Yuan J,Tariq M,Li N,Sun H,Wang H,Zhang X,Chen J,Bao X,Jauch R

Fri Apr 17 00:00:00 EDT 2020

Nuclear Exosome Targeting Complex Core Factor Zcchc8 Regulates the Degradation of LINE1 RNA in Early Embryos and Embryonic Stem Cells.

Cell reports

Wu Y,Liu W,Chen J,Liu S,Wang M,Yang L,Chen C,Qi M,Xu Y,Qiao Z,Yan R,Kou X,Zhao Y,Shen B,Yin J,Wang H,Gao Y,Gao S

Tue Nov 19 00:00:00 EST 2019

mRNAs are sorted for export or degradation before passing through nuclear speckles.

Nucleic acids research

Fan J,Kuai B,Wang K,Wang L,Wang Y,Wu X,Chi B,Li G,Cheng H

Wed Sep 19 00:00:00 EDT 2018

mRNAs are sorted for export or degradation before passing through nuclear speckles.

Nucleic acids research

Fan J,Kuai B,Wang K,Wang L,Wang Y,Wu X,Chi B,Li G,Cheng H

Wed Sep 19 00:00:00 EDT 2018

生物信息学

蛋白别名: DKFZp434E2220; TRAMP-like complex RNA-binding factor ZCCHC8; Zinc finger CCHC domain-containing protein 8; zinc finger, CCHC domain containing 8

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基因别名: 5730565F05Rik; ZCCHC8

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UniProt ID: (Human) Q6NZY4, (Mouse) Q9CYA6

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Entrez Gene ID: (Human) 55596, (Mouse) 70650

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功能

protein binding zinc ion binding poly(A) RNA binding nucleic acid binding metal ion binding RNA metabolism protein

参与通路

mRNA splicing, via spliceosome mRNA processing biological_process RNA splicing