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This antibody is predicted to react with bovine based on sequence homology.
Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane. This affects rapid intracellular signaling by sex hormones via ERK and AKT kinases and the generation of cAMP, but does not affect that mediated by their nuclear receptor. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DHHC domain-containing cysteine-rich protein 21; DHHC-21; DHHC21; GABA-A receptor-associated membrane protein 3; Palmitoyltransferase ZDHHC21; probable palmitoyltransferase ZDHHC21; Zinc finger DHHC domain-containing protein 21; zinc finger, DHHC domain containing 21; zinc finger, DHHC-type containing 21
基因别名: 9130404H11Rik; AL024349; D130004H04Rik; dep; DHHC-21; DHHC21; DNZ1; Gramp3; HSPC097; ZDHHC21
UniProt ID: (Human) Q8IVQ6, (Mouse) Q9D270
Entrez Gene ID: (Human) 340481, (Mouse) 68268