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Antibody detects endogenous levels of total ZFYVE27.
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protrudin; RP11-459F3.2; Spastic paraplegia 33 protein; zinc finger FYVE domain containing 27; Zinc finger FYVE domain-containing protein 27; zinc finger, FYVE domain containing 27
基因别名: 2210011N02Rik; 9530077C24Rik; AI426636; AI593546; AI835681; PROTRUDIN; SPG33; ZFYVE27
UniProt ID: (Human) Q5T4F4, (Rat) Q6P7B7, (Mouse) Q3TXX3
Entrez Gene ID: (Human) 118813, (Rat) 309376, (Mouse) 319740
分子生物学功能:
membrane traffic protein
membrane trafficking regulatory protein