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产品信息
H00007545-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
3F7
抗原
ZIC1 (NP_003403, 2 a.a. approximately 95 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.41 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: LLDAGPQYPA IGVTTFGASR HHSAGDVAER DVGLGINPFA DGMGAFKLNP SSHELASAGQ TAFTSQAPGY AAAAALGHHH HPGHVGSYSS AAFN
靶标信息
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Zic family member 1 (odd-paired homolog, Drosophila); Zinc finger protein 201; Zinc finger protein of the cerebellum 1; Zinc finger protein ZIC 1
基因别名: CRS6; ZIC; ZIC1; ZNF201
UniProt ID: (Human) Q15915
Entrez Gene ID: (Human) 7545
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
metal ion binding
C2H2 zinc finger transcription factor
transcription from RNA polymerase II promoter
pattern specification process
brain development
adult walking behavior
regulation of smoothened signaling pathway
spinal cord development
cell differentiation
positive regulation of protein import into nucleus
inner ear morphogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
