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Immunogen sequence: MEAAETEAEA AALEVLAEVA GILEPVGLQE EAELPAKILV EFVVDSQKKD KLLCSQLQVA DFLQNILAQE DTAKGLDPLA SEDTSRQKAI AAKEQWKELK ATYREHVEAI KIGLTKALTQ MEEAQRKRTQ LREAFEQLQA KKQMAMEKRR AVQNQWQLQQ EKHLQHLAEV SAEVRERKTG TQQELDRVFQ KLGNLKQQAE QERDKLQRYQ TFLQLLYTLQ GKLLFPEAEA EAENLPDDKP QQPTRPQEQS TGDTMGRDPG VSFKAVGLQP AGDVNLP; Positive Samples: 293T, SW620, HepG2, Jurkat, Mouse brain; Cellular Location: Chromosome, Nucleus, centromere, kinetochore
This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: human ZW10 interacting protein-1; neuroprotective protein 8; Scoilin; SNAP25 interacting protein 30; SNAP25 interacting protein of 30 kDa; SNAP25-interacting protein 30; ZW10 interacting protein-1; ZW10 interactor; ZW10 interactor, kinetochore protein; ZW10-interacting protein 1; Zwint-1
基因别名: 2010007E07Rik; 2600001N01Rik; D10Ertd749e; HZwint-1; KNTC2AP; SIP30; ZWINT; Zwint-1; ZWINT1
UniProt ID: (Human) O95229, (Rat) Q8VIL3, (Mouse) Q9CQU5
Entrez Gene ID: (Human) 11130, (Rat) 257644, (Mouse) 52696