Product References
Structural and functional analysis of salivary intercalated duct cells reveals a secretory phenotype.
The Journal of physiology
Wahl AM,Takano T,Su S,Warner BM,Perez P,Sneyd J,Yule DI
PA1-920A was used in Immunohistochemistry to reveal that the intercalated duct cells lack proteins vital for reabsorption and express proteins necessary for secretion.
Sun Oct 01 00:00:00 UTC 2023
A Mathematical Model of Salivary Gland Duct Cells.
Bulletin of mathematical biology
Su S,Rugis J,Wahl A,Doak S,Li Y,Suresh V,Yule D,Sneyd J
PA1-920A was used in Immunohistochemistry to show that saliva production is not sensitive to structural variation of the duct.
Thu Jul 07 00:00:00 UTC 2022
The microbiota-gut-kidney axis mediates host osmoregulation in a small desert mammal.
NPJ biofilms and microbiomes
Nouri Z,Zhang XY,Khakisahneh S,Degen AA,Wang DH
PA1-920A was used in Western Blot to highlight a vital role of the microbiota-gut-kidney axis in mediating salt-related osmoregulation, allowing small mammals to adapt to high salt loads in a desert habitat.
Mon Apr 04 00:00:00 UTC 2022
MiR-199a-3p in mouse bone marrow mesenchymal stem cell exosomes increases epithelial sodium channel expression in lung injury.
Fundamental & clinical pharmacology
Chen L,Hou Y,Du D,Cui Y,Nie H,Ding Y
PA1-920A was used in Immunocytochemistry and Western Blotting to show that the BMSC-exo could participate in the regulation of ENaC through miR-199a-3p originated from BMSC-exo, thereby providing a new pharmacological tool for the treatment of ALI.
Thu Dec 01 00:00:00 UTC 2022
MiR-199a-3p in mouse bone marrow mesenchymal stem cell exosomes increases epithelial sodium channel expression in lung injury.
Fundamental & clinical pharmacology
Chen L,Hou Y,Du D,Cui Y,Nie H,Ding Y
PA1-920A was used in Immunocytochemistry and Western Blotting to show that the BMSC-exo could participate in the regulation of ENaC through miR-199a-3p originated from BMSC-exo, thereby providing a new pharmacological tool for the treatment of ALI.
Thu Dec 01 00:00:00 UTC 2022
VX-809 mitigates disease in a mouse model of autosomal dominant polycystic kidney disease bearing the R3277C human mutation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Yanda MK,Cebotaru L
PA1-920A was used in Immunocytochemistry-immunoflourescence to test VX-809 in RC/RC mice bearing the R3277C human mutation to demonstrate its therapeutic potential.
Mon Nov 01 00:00:00 UTC 2021
Alcohol inhibits alveolar fluid clearance through the epithelial sodium channel via the A2 adenosine receptor in acute lung injury.
Molecular medicine reports
Deng W,He J,Tang XM,Li CY,Tong J,Qi D,Wang DX
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Western Blot
Fri Oct 01 00:00:00 UTC 2021
Ferulic acid ameliorates lipopolysaccharide-induced tracheal injury via cGMP/PKGII signaling pathway.
Respiratory research
Xie X,Yu T,Hou Y,Han A,Ding Y,Nie H,Cui Y
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Western Blot
Sat Dec 04 00:00:00 UTC 2021
Ferulic acid ameliorates lipopolysaccharide-induced tracheal injury via cGMP/PKGII signaling pathway.
Respiratory research
Xie X,Yu T,Hou Y,Han A,Ding Y,Nie H,Cui Y
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Western Blot
Sat Dec 04 00:00:00 UTC 2021
Melatonin Attenuates Sepsis-Induced Acute Lung Injury Through Improvement of Epithelial Sodium Channel-Mediated Alveolar Fluid Clearance Via Activation of SIRT1/SGK1/Nedd4-2 Signaling Pathway.
Frontiers in pharmacology
Li J,Liu L,Zhou X,Lu X,Liu X,Li G,Long J
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Immunocytochemistry
Tue Dec 29 00:00:00 UTC 2020
Melatonin Attenuates Sepsis-Induced Acute Lung Injury Through Improvement of Epithelial Sodium Channel-Mediated Alveolar Fluid Clearance Via Activation of SIRT1/SGK1/Nedd4-2 Signaling Pathway.
Frontiers in pharmacology
Li J,Liu L,Zhou X,Lu X,Liu X,Li G,Long J
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Immunocytochemistry
Tue Dec 29 00:00:00 UTC 2020
Melatonin Attenuates Sepsis-Induced Acute Lung Injury Through Improvement of Epithelial Sodium Channel-Mediated Alveolar Fluid Clearance Via Activation of SIRT1/SGK1/Nedd4-2 Signaling Pathway.
Frontiers in pharmacology
Li J,Liu L,Zhou X,Lu X,Liu X,Li G,Long J
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Immunocytochemistry
Tue Dec 29 00:00:00 UTC 2020
Melatonin Attenuates Sepsis-Induced Acute Lung Injury Through Improvement of Epithelial Sodium Channel-Mediated Alveolar Fluid Clearance Via Activation of SIRT1/SGK1/Nedd4-2 Signaling Pathway.
Frontiers in pharmacology
Li J,Liu L,Zhou X,Lu X,Liu X,Li G,Long J
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Immunocytochemistry
Tue Dec 29 00:00:00 UTC 2020
Bone marrow mesenchymal stem cells derived miRNA-130b enhances epithelial sodium channel by targeting PTEN.
Respiratory research
Zhang H,Ding Y,Hou Y,Liu Y,Zhou Z,Nie H
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Western Blot
Fri Dec 11 00:00:00 UTC 2020
Bone marrow mesenchymal stem cells derived miRNA-130b enhances epithelial sodium channel by targeting PTEN.
Respiratory research
Zhang H,Ding Y,Hou Y,Liu Y,Zhou Z,Nie H
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Western Blot
Fri Dec 11 00:00:00 UTC 2020
Bone marrow mesenchymal stem cell-conditioned medium facilitates fluid resolution via miR-214-activating epithelial sodium channels.
MedComm
Ding Y,Cui Y,Hou Y,Nie H
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Western Blot
Tue Dec 01 00:00:00 UTC 2020
"Reversed polarization" of Na/K-ATPase-a sign of inverted transport in the human endolymphatic sac: a super-resolution structured illumination microscopy (SR-SIM) study.
Cell and tissue research
Nordström CK,Danckwardt-Lillieström N,Liu W,Rask-Andersen H
PA1-920A was used in Immunohistochemistry to analyse the ion transport protein sodium/potassium-ATPase (Na/K-ATPase) and its isoforms in the human endolymphatic sac (ES) using super-resolution structured illumination microscopy (SR-SIM).
Sun Mar 01 00:00:00 UTC 2020
Patient-derived pancreas-on-a-chip to model cystic fibrosis-related disorders.
Nature communications
Shik Mun K,Arora K,Huang Y,Yang F,Yarlagadda S,Ramananda Y,Abu-El-Haija M,Palermo JJ,Appakalai BN,Nathan JD,Naren AP
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Immunohistochemistry
Tue Jul 16 00:00:00 UTC 2019
Upregulation of the WNK4 Signaling Pathway Inhibits Epithelial Sodium Channels of Mouse Tracheal Epithelial Cells After Influenza A Infection.
Frontiers in pharmacology
Hou Y,Cui Y,Zhou Z,Liu H,Zhang H,Ding Y,Nie H,Ji HL
PA1-920A was used in Western Blotting to examine the effects of influenza virus infection on epithelial sodium channel activity in mouse tracheal epithelial cells.
Thu Oct 01 00:00:00 UTC 2020
The Epithelial Sodium Channel (αENaC) Is a Downstream Therapeutic Target of ASCL1 in Pulmonary Neuroendocrine Tumors.
Translational oncology
He M,Liu S,Gallolu Kankanamalage S,Borromeo MD,Girard L,Gazdar AF,Minna JD,Johnson JE,Cobb MH
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Immunocytochemistry
Sun Apr 01 00:00:00 UTC 2018
An angiotensin II type 1 receptor binding molecule has a critical role in hypertension in a chronic kidney disease model.
Kidney international
Kobayashi R,Wakui H,Azushima K,Uneda K,Haku S,Ohki K,Haruhara K,Kinguchi S,Matsuda M,Ohsawa M,Toya Y,Nishiyama A,Yamashita A,Tanabe K,Maeshima Y,Umemura S,Tamura K
PA1-920A was used in Western Blotting to provide evidence that renal Angiotensin II type 1 receptor-associated protein plays a critical role in suppressing hypertension in a mouse remnant kidney model of chronic kidney disease.
Mon May 01 00:00:00 UTC 2017
Dexmedetomidine enhances human lung fluid clearance through improving alveolar sodium transport.
Fundamental & clinical pharmacology
Cui Y,Ding Y,Chen L,Li Y,Li YC,Nie H
PA1920A was used in western blot to elucidate the mechanisms of dexmedetomidine treatment on human alveolar fluid transport
Tue Aug 01 00:00:00 UTC 2017
Novel mechanisms for crotonaldehyde-induced lung edema.
Oncotarget
Li Y,Chang J,Cui Y,Zhao R,Ding Y,Hou Y,Zhou Z,Ji HL,Nie H
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Western Blot
Fri Oct 13 00:00:00 UTC 2017
Amiloride Improves Endothelial Function and Reduces Vascular Stiffness in Female Mice Fed a Western Diet.
Frontiers in physiology
Martinez-Lemus LA,Aroor AR,Ramirez-Perez FI,Jia G,Habibi J,DeMarco VG,Barron B,Whaley-Connell A,Nistala R,Sowers JR
PA1-920A was used in Immunohistochemistry-immunofluorescence to determine the effect that reducing epithelial Na+channel activity with a very-low-dose of amiloride would have on decreasing endothelial and arterial stiffness in young female mice consuming a Western diet.
Thu Oct 01 00:00:00 UTC 2020
Regulation of mechanosensitive biliary epithelial transport by the epithelial Na(+) channel.
Hepatology (Baltimore, Md.)
Li Q,Kresge C,Bugde A,Lamphere M,Park JY,Feranchak AP
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Immunohistochemistry (Paraffin)
Mon Feb 01 00:00:00 UTC 2016
Regulation of mechanosensitive biliary epithelial transport by the epithelial Na(+) channel.
Hepatology (Baltimore, Md.)
Li Q,Kresge C,Bugde A,Lamphere M,Park JY,Feranchak AP
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Immunohistochemistry (Paraffin)
Mon Feb 01 00:00:00 UTC 2016
Formaldehyde impairs transepithelial sodium transport.
Scientific reports
Cui Y,Li H,Wu S,Zhao R,Du D,Ding Y,Nie H,Ji HL
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Western Blot
Thu Oct 20 00:00:00 UTC 2016
Renal tubule angiotensin II type 1 receptor-associated protein promotes natriuresis and inhibits salt-sensitive blood pressure elevation.
Journal of the American Heart Association
Wakui H,Uneda K,Tamura K,Ohsawa M,Azushima K,Kobayashi R,Ohki K,Dejima T,Kanaoka T,Tsurumi-Ikeya Y,Matsuda M,Haruhara K,Nishiyama A,Yabana M,Fujikawa T,Yamashita A,Umemura S
PA1-920A was used in western blot to study the effects of ATRAP in the renal distal tubules in response to high salt treatment using wild type and ATRAP transgenic mice
Thu Mar 19 00:00:00 UTC 2015
Endothelial Gata5 transcription factor regulates blood pressure.
Nature communications
Messaoudi S,He Y,Gutsol A,Wight A,Hébert RL,Vilmundarson RO,Makrigiannis AP,Chalmers J,Hamet P,Tremblay J,McPherson R,Stewart AFR,Touyz RM,Nemer M
PA1-920A was used in western blot to test if GATA5 is a regulator of blood pressure
Mon Nov 30 00:00:00 UTC 2015
Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension.
Kidney international
Ohsawa M,Tamura K,Wakui H,Maeda A,Dejima T,Kanaoka T,Azushima K,Uneda K,Tsurumi-Ikeya Y,Kobayashi R,Matsuda M,Uchida S,Toya Y,Kobori H,Nishiyama A,Yamashita A,Ishikawa Y,Umemura S
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Western Blot
Mon Sep 01 00:00:00 UTC 2014
Cholera toxin enhances Na(+) absorption across MCF10A human mammary epithelia.
American journal of physiology. Cell physiology
Wang Q,Schultz BD
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Western Blot
Sat Mar 01 00:00:00 UTC 2014
Filamin interacts with epithelial sodium channel and inhibits its channel function.
The Journal of biological chemistry
Wang Q,Dai XQ,Li Q,Tuli J,Liang G,Li SS,Chen XZ
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Immunocytochemistry
Fri Jan 04 00:00:00 UTC 2013
Filamin interacts with epithelial sodium channel and inhibits its channel function.
The Journal of biological chemistry
Wang Q,Dai XQ,Li Q,Tuli J,Liang G,Li SS,Chen XZ
Published figure using alpha-ENaC polyclonal antibody (Product # PA1-920A) in Immunocytochemistry
Fri Jan 04 00:00:00 UTC 2013
Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells.
American journal of physiology. Lung cellular and molecular physiology
Rubenstein RC,Lockwood SR,Lide E,Bauer R,Suaud L,Grumbach Y
PA1-920A was used in western blot to investigate the role of CFTR in the modulation of epithelial sodium channel expression and function
Sat Jan 01 00:00:00 UTC 2011
Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung.
American journal of physiology. Lung cellular and molecular physiology
Lazrak A,Jurkuvenaite A,Chen L,Keeling KM,Collawn JF,Bedwell DM,Matalon S
PA1-920A was used in western blot to study the inverse relationship between alveolar epithelial sodium channel activity and cystic fibrosis transmembrane conductance regulator expression in mice
Sat Oct 01 00:00:00 UTC 2011
Long-term terbutaline exposure stimulates alpha1-Na+-K+-ATPase expression at posttranscriptional level in rat fetal distal lung epithelial cells.
American journal of physiology. Lung cellular and molecular physiology
Rahman MS,Gandhi S,Otulakowski G,Duan W,Sarangapani A,O'Brodovich H
PA1-920A was used in western blot to determine the effect of long-term terbutaline treatment on steady-state expression levels of ENaC in rat fetal distal lung epithelial cells
Fri Jan 01 00:00:00 UTC 2010
Interleukin-6 stimulates epithelial sodium channels in mouse cortical collecting duct cells.
American journal of physiology. Regulatory, integrative and comparative physiology
Li K,Guo D,Zhu H,Hering-Smith KS,Hamm LL,Ouyang J,Dong Y
PA1-920A was used in western blot to investigate the effect of interleukin-6 on epithelial sodium channel function in mouse cortical collecting duct cells
Sun Aug 01 00:00:00 UTC 2010
The carboxyl terminus of the alpha-subunit of the amiloride-sensitive epithelial sodium channel binds to F-actin.
The Journal of biological chemistry
Mazzochi C,Bubien JK,Smith PR,Benos DJ
PEP-088 was used in western blot to study the interaction of amiloride-sensitive epithelial sodium channel and F-actin
Fri Mar 10 00:00:00 UTC 2006