Product References
Three-dimensional structured illumination microscopy with enhanced axial resolution.
Nature biotechnology
Li X,Wu Y,Su Y,Rey-Suarez I,Matthaeus C,Updegrove TB,Wei Z,Zhang L,Sasaki H,Li Y,Guo M,Giannini JP,Vishwasrao HD,Chen J,Lee SJ,Shao L,Liu H,Ramamurthi KS,Taraska JW,Upadhyaya A,La Riviere P,Shroff H
32-2500 was used in Immunocytochemistry-immunofluorescence to present two distinct, complementary methods to improve axial resolution in 3D SIM with minimal or no modification to the optical system.
Fri Sep 01 00:00:00 EDT 2023
Modest increase of KIF11 expression exposes fragilities in the mitotic spindle, causing chromosomal instability.
Journal of cell science
Dale KL,Armond JW,Hynds RE,Vladimirou E
32-2500 was used in Western Blot, Immunocytochemistry to investigate the molecular and mechanistic basis of Chromosomal instability initiation.
Thu Sep 01 00:00:00 EDT 2022
Modest increase of KIF11 expression exposes fragilities in the mitotic spindle, causing chromosomal instability.
Journal of cell science
Dale KL,Armond JW,Hynds RE,Vladimirou E
32-2500 was used in Western Blot, Immunocytochemistry to investigate the molecular and mechanistic basis of Chromosomal instability initiation.
Thu Sep 01 00:00:00 EDT 2022
The receptor kinase SRF3 coordinates iron-level and flagellin dependent defense and growth responses in plants.
Nature communications
Platre MP,Satbhai SB,Brent L,Gleason MF,Cao M,Grison M,Glavier M,Zhang L,Gaillochet C,Goeschl C,Giovannetti M,Enugutti B,Neveu J,von Reth M,Alcázar R,Parker JE,Vert G,Bayer E,Busch W
32-2500 was used in Western Blotting to report a receptor kinase SRF3, with a role in coordinating root growth, iron homeostasis and immunity pathways via regulation of callose synthases.
Mon Aug 01 00:00:00 EDT 2022
Incorporating the image formation process into deep learning improves network performance.
Nature methods
Li Y,Su Y,Guo M,Han X,Liu J,Vishwasrao HD,Li X,Christensen R,Sengupta T,Moyle MW,Rey-Suarez I,Chen J,Upadhyaya A,Usdin TB,Colón-Ramos DA,Liu H,Wu Y,Shroff H
32-2500 was used in Immunocytochemistry-immunofluorescence to demonstrate RLN's performance on cells, tissues and embryos imaged with widefield-, light-sheet-, confocal- and super-resolution microscopy.
Tue Nov 01 00:00:00 EDT 2022
Understanding In Vitro Pathways to Drug Discovery for TDP-43 Proteinopathies.
International journal of molecular sciences
Cheng HWA,Callis TB,Montgomery AP,Danon JJ,Jorgensen WT,Ke YD,Ittner LM,Werry EL,Kassiou M
32-2500 was used in Immunocytochemistry, Western Blot to highlight the challenges of using cellular models in lead development during drug discovery for ALS and FTD and reinforces the need to perform assessments of novel therapeutics across a variety of cell lines and aetiological models.
Fri Nov 25 00:00:00 EST 2022
Volumetric interferometric lattice light-sheet imaging.
Nature biotechnology
Cao B,Coelho S,Li J,Wang G,Pertsinidis A
32-2500 was used in Immunocytochemistry-immunoflourescence to present 3D interferometric lattice light-sheet (3D-iLLS) imaging, a technique that requires low excitation light levels and provides high background suppression and substantially improved volumetric resolution by combining 4Pi interferometry with selective plane illumination.
Mon Nov 01 00:00:00 EDT 2021
An immune-competent, replication-permissive Syrian Hamster glioma model for evaluating Delta-24-RGD oncolytic adenovirus.
Neuro-oncology
Phillips LM,Li S,Gumin J,Daou M,Ledbetter D,Yang J,Singh S,Parker Kerrigan BC,Hossain A,Yuan Y,Gomez-Manzano C,Fueyo J,Lang FF
32-2500 was used in Western Blotting to develop the first intracranial glioma model that is both adenovirus replication-permissive and immunocompetent.
Tue Nov 02 00:00:00 EDT 2021
Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis.
Cellular and molecular life sciences : CMLS
Ranea-Robles P,Violante S,Argmann C,Dodatko T,Bhattacharya D,Chen H,Yu C,Friedman SL,Puchowicz M,Houten SM
32-2500 was used in Western Blotting to conclude that EHHADH plays an essential role in the metabolism of medium-chain DCAs and postulate that peroxisomal DCA β-oxidation is a regulator of hepatic cholesterol biosynthesis.
Thu Jul 01 00:00:00 EDT 2021
Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis.
Cellular and molecular life sciences : CMLS
Ranea-Robles P,Violante S,Argmann C,Dodatko T,Bhattacharya D,Chen H,Yu C,Friedman SL,Puchowicz M,Houten SM
32-2500 was used in Western Blotting to conclude that EHHADH plays an essential role in the metabolism of medium-chain DCAs and postulate that peroxisomal DCA β-oxidation is a regulator of hepatic cholesterol biosynthesis.
Thu Jul 01 00:00:00 EDT 2021
Modulation of protein phosphatase 1 gamma 2 during cell division of cervical cancer HeLa cells.
Contemporary oncology (Poznan, Poland)
Agnihotri SK,Kar P,Singh M,Pant G,Mitra K,Bhatt MLB,Sachdev M
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Immunocytochemistry
Wed Apr 27 00:00:00 EDT 2022
Modulation of protein phosphatase 1 gamma 2 during cell division of cervical cancer HeLa cells.
Contemporary oncology (Poznan, Poland)
Agnihotri SK,Kar P,Singh M,Pant G,Mitra K,Bhatt MLB,Sachdev M
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Immunocytochemistry
Wed Apr 27 00:00:00 EDT 2022
Expansion Microscopy Reveals Plasmodium falciparum Blood-Stage Parasites Undergo Anaphase with A Chromatin Bridge in the Absence of Mini-Chromosome Maintenance Complex Binding Protein.
Microorganisms
Liffner B,Absalon S
32-2500 was used in Immunohistochemistry to investigate the role of microtubules following mini-chromosome maintenance complex binding-protein depletion and study the nuclear envelope in Plasmodium falciparum.
Sat Nov 06 00:00:00 EDT 2021
Expansion Microscopy Reveals Plasmodium falciparum Blood-Stage Parasites Undergo Anaphase with A Chromatin Bridge in the Absence of Mini-Chromosome Maintenance Complex Binding Protein.
Microorganisms
Liffner B,Absalon S
32-2500 was used in Immunohistochemistry to investigate the role of microtubules following mini-chromosome maintenance complex binding-protein depletion and study the nuclear envelope in Plasmodium falciparum.
Sat Nov 06 00:00:00 EDT 2021
Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice.
Kidney360
Ranea-Robles P,Portman K,Bender A,Lee K,He JC,Mulholland DJ,Argmann C,Houten SM
32-2500 was used in Western Blot to assess the role of androgens in the kidney phenotype of Ehhadh KO mice.
Wed Sep 01 00:00:00 EDT 2021
Combined Targeting of PARG and Wee1 Causes Decreased Cell Survival and DNA Damage in an S-Phase-Dependent Manner.
Molecular cancer research : MCR
Agostini LC,Jain A,Shupp A,Nevler A,McCarthy G,Bussard KM,Yeo CJ,Brody JR
32-2500 was used in Immunocytochemistry, Western Blot to demonstrate the efficacy and mechanism of action of targeting both PARG and Wee1 in PDAC and colorectal carcinoma cells.
Mon Feb 01 00:00:00 EST 2021
Rapid image deconvolution and multiview fusion for optical microscopy.
Nature biotechnology
Guo M,Li Y,Su Y,Lambert T,Nogare DD,Moyle MW,Duncan LH,Ikegami R,Santella A,Rey-Suarez I,Green D,Beiriger A,Chen J,Vishwasrao H,Ganesan S,Prince V,Waters JC,Annunziata CM,Hafner M,Mohler WA,Chitnis AB,Upadhyaya A,Usdin TB,Bao Z,Colón-Ramos D,La Riviere P,Liu H,Wu Y,Shroff H
32-2500 was used in Immunocytochemistry to describe theoretical and practical advances in algorithm and software design that result in image processing times that are tenfold to several thousand fold faster than with previous methods.
Sun Nov 01 00:00:00 EDT 2020
Biallelic variants in MAATS1 encoding CFAP91, a calmodulin-associated and spoke-associated complex protein, cause severe astheno-teratozoospermia and male infertility.
Journal of medical genetics
Martinez G,Beurois J,Dacheux D,Cazin C,Bidart M,Kherraf ZE,Robinson DR,Satre V,Le Gac G,Ka C,Gourlaouen I,Fichou Y,Petre G,Dulioust E,Zouari R,Thierry-Mieg N,Touré A,Arnoult C,Bonhivers M,Ray P,Coutton C
32-2500 was used in Immunocytochemistry to identify uncharacterised gene defects account for MMAF.
Thu Oct 01 00:00:00 EDT 2020
Slc22a5 haploinsufficiency does not aggravate the phenotype of the long-chain acyl-CoA dehydrogenase KO mouse.
Journal of inherited metabolic disease
Ranea-Robles P,Yu C,van Vlies N,Vaz FM,Houten SM
32-2500 was used in Western Blotting to investigate if carnitine deficiency and/or acylcarnitine accumulation play a role in the pathophysiology of fatty acid oxidation disorders.
Fri May 01 00:00:00 EDT 2020
Extracellular acidity‑induced expression of Kallikrein‑related peptidases 7 and 8 is involved in increased invasiveness of gastric cancer cells.
Oncology reports
Lim SC,Kee KH,Lee MJ,Hong R,Han SI
32-2500 was used in Western Blotting to indicate that tumor invasion enhancement by extracellular acidity is regulated at least in part through the induction of the COX/KLK7 and KLK8 axis in gastric cancer cells.
Fri May 01 00:00:00 EDT 2020
UHPLC-Q/Orbitrap/MS/MS fingerprinting and antitumoral effects of Prosopis strombulifera (LAM.) BENTH. queous extract on allograft colorectal and melanoma cancer models.
Heliyon
Persia FA,Troncoso ME,Rinaldini E,Simirgiotis M,Tapia A,Bórquez J,Mackern-Oberti JP,Hapon MB,Gamarra-Luques C
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Western Blot
Sat Feb 01 00:00:00 EST 2020
Hippo-YAP1 Is a Prognosis Marker and Potentially Targetable Pathway in Advanced Gallbladder Cancer.
Cancers
García P,Rosa L,Vargas S,Weber H,Espinoza JA,Suárez F,Romero-Calvo I,Elgueta N,Rivera V,Nervi B,Obreque J,Leal P,Viñuela E,Aguayo G,Muñiz S,Sagredo A,Roa JC,Bizama C
32-2500 was used in Western Blotting to demonstrate that key components of the Hippo-YAP1 signaling pathway are dysregulated in advanced gallbladder cancer.
Wed Mar 25 00:00:00 EDT 2020
Hippo-YAP1 Is a Prognosis Marker and Potentially Targetable Pathway in Advanced Gallbladder Cancer.
Cancers
García P,Rosa L,Vargas S,Weber H,Espinoza JA,Suárez F,Romero-Calvo I,Elgueta N,Rivera V,Nervi B,Obreque J,Leal P,Viñuela E,Aguayo G,Muñiz S,Sagredo A,Roa JC,Bizama C
32-2500 was used in Western Blotting to demonstrate that key components of the Hippo-YAP1 signaling pathway are dysregulated in advanced gallbladder cancer.
Wed Mar 25 00:00:00 EDT 2020
An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin Polymerization.
ACS infectious diseases
Ullah I,Gahalawat S,Booshehri LM,Niederstrasser H,Majumdar S,Leija C,Bradford JM,Hu B,Ready JM,Wetzel DM
32-2500 was used in Western Blot to demonstrate that MMV676477 is a potent antiparasitic compound that preferentially promotes Leishmania microtubule polymerization.
Fri Aug 14 00:00:00 EDT 2020
Antitumor Effects of Anti-Semaphorin 4D Antibody Unravel a Novel Proinvasive Mechanism of Vascular-Targeting Agents.
Cancer research
Zuazo-Gaztelu I,Pàez-Ribes M,Carrasco P,Martín L,Soler A,Martínez-Lozano M,Pons R,Llena J,Palomero L,Graupera M,Casanovas O
32-2500 was used in Western Blotting to investigate the effect vascular-targeting agent, anti-semaphorin-4D has on reducing tumor growth and extending survival in the RIP1-Tag2 model but also unravels a novel promalignant effect involving macrophage-derived SDF1 that promotes tumor invasion and metastasis, both in animal models and patients.
Tue Oct 15 00:00:00 EDT 2019
RNA-Binding Protein HuR Regulates Both Mutant and Wild-Type IDH1 in IDH1-Mutated Cancer.
Molecular cancer research : MCR
Zarei M,Lal S,Vaziri-Gohar A,O'Hayer K,Gunda V,Singh PK,Brody JR,Winter JM
32-2500 was used in Western Blotting to demonstrate that the HuR-IDH1 (mutant and wild-type IDH1) regulatory axis is a critical, actionable therapeutic target in IDH1-mutated cancer, and incomplete blockade of the entire HuR-IDH1 survival axis would likely diminish the efficacy of drugs that selectively target only the mutant isoenzyme.
Fri Feb 01 00:00:00 EST 2019
Selective defects in gene expression control genome instability in yeast splicing mutants.
Molecular biology of the cell
Tam AS,Sihota TS,Milbury KL,Zhang A,Mathew V,Stirling PC
32-2500 was used in Western Blotting to characterise genome instability phenotypes in yeast splicing factor mutants.
Tue Jan 15 00:00:00 EST 2019
The transcription factor TFCP2L1 induces expression of distinct target genes and promotes self-renewal of mouse and human embryonic stem cells.
The Journal of biological chemistry
Wang X,Wang X,Zhang S,Sun H,Li S,Ding H,You Y,Zhang X,Ye SD
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Western Blot
Fri Apr 12 00:00:00 EDT 2019
The transcription factor TFCP2L1 induces expression of distinct target genes and promotes self-renewal of mouse and human embryonic stem cells.
The Journal of biological chemistry
Wang X,Wang X,Zhang S,Sun H,Li S,Ding H,You Y,Zhang X,Ye SD
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Western Blot
Fri Apr 12 00:00:00 EDT 2019
Involvement of Hsp90 and cyclophilins in intoxication by AIP56, a metalloprotease toxin from Photobacterium damselae subsp. piscicida.
Scientific reports
Rodrigues IS,Pereira LMG,Lisboa J,Pereira C,Oliveira P,Dos Santos NMS,do Vale A
32-2500 was used in Western Blotting to explore the mechanisms through which the metalloprotease toxin AIP56 from Photobacterium damselae subsp. piscicida. causes intoxication, with specific focus on its interaction with host Hsp90 and cyclophilins.
Fri Jun 21 00:00:00 EDT 2019
Neonatal maternal deprivation impairs localized de novo activity-induced protein translation at the synapse in the rat hippocampus.
Bioscience reports
Ahmad F,Salahuddin M,Alsamman K,Herzallah HK,Al-Otaibi ST
32-2500 was used in Western Blotting to elucidate the molecular mechanisms underlying the detrimental alterations in brain functions induced by early-life stress.
Fri Jun 29 00:00:00 EDT 2018
Fish Oil Supplementation Reduces Inflammation but Does Not Restore Renal Function and Klotho Expression in an Adenine-Induced CKD Model.
Nutrients
Henao Agudelo JS,Baia LC,Ormanji MS,Santos ARP,Machado JR,Saraiva Câmara NO,Navis GJ,de Borst MH,Heilberg IP
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Western Blot
Tue Sep 11 00:00:00 EDT 2018
Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.
The Journal of biological chemistry
Ždralević M,Brand A,Di Ianni L,Dettmer K,Reinders J,Singer K,Peter K,Schnell A,Bruss C,Decking SM,Koehl G,Felipe-Abrio B,Durivault J,Bayer P,Evangelista M,O'Brien T,Oefner PJ,Renner K,Pouysségur J,Kreutz M
32-2500 was used in Western Blotting to establish the role of lactate dehydrogenase A in tumour growth in aggressive cancers.
Fri Oct 12 00:00:00 EDT 2018
A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3α and GSK3β in Regulating Embryonic Stem Cell Fate.
Developmental cell
Chen X,Wang R,Liu X,Wu Y,Zhou T,Yang Y,Perez A,Chen YC,Hu L,Chadarevian JP,Assadieskandar A,Zhang C,Ying QL
32-2500 was used in Western Blotting to show that Glycogen synthase kinase 3 (GSK3)α and GSK3Β can be selectively inhibited in mouse embryonic stem cells using a chemical-genetic approach.
Mon Dec 04 00:00:00 EST 2017
Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells.
Cancer research
Zarei M,Lal S,Parker SJ,Nevler A,Vaziri-Gohar A,Dukleska K,Mambelli-Lisboa NC,Moffat C,Blanco FF,Chand SN,Jimbo M,Cozzitorto JA,Jiang W,Yeo CJ,Londin ER,Seifert EL,Metallo CM,Brody JR,Winter JM
32-2500 was used in Western Blotting to highlight the HuR-IDH1 regulatory axis as a critical, actionable therapeutic target in pancreatic cancer.
Tue Aug 15 00:00:00 EDT 2017
RECQ-like helicases Sgs1 and BLM regulate R-loop-associated genome instability.
The Journal of cell biology
Chang EY,Novoa CA,Aristizabal MJ,Coulombe Y,Segovia R,Chaturvedi R,Shen Y,Keong C,Tam AS,Jones SJM,Masson JY,Kobor MS,Stirling PC
32-2500 was used in Western Blotting to show that SGS1 loss increases R-loop accumulation and sensitises cells to transcription-replication collisions.
Mon Dec 04 00:00:00 EST 2017
A DII Domain-Based Auxin Reporter Uncovers Low Auxin Signaling during Telophase and Early G1.
Plant physiology
Mir R,Aranda LZ,Biaocchi T,Luo A,Sylvester AW,Rasmussen CG
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Western Blot
Sun Jan 01 00:00:00 EST 2017
Hili Inhibits HIV Replication in Activated T Cells.
Journal of virology
Peterlin BM,Liu P,Wang X,Cary D,Shao W,Leoz M,Hong T,Pan T,Fujinaga K
32-2500 was used in Western Blotting to study the effects of human P-element-induced wimpy-like 2 on the replication of HIV in activated CD4+ T cells.
Thu Jun 01 00:00:00 EDT 2017
TFCP2L1 represses multiple lineage commitment of mouse embryonic stem cells through MTA1 and LEF1.
Journal of cell science
Liu K,Zhang Y,Liu D,Ying QL,Ye S
32-2500 was used in Western Blotting to study the effects of Tfcp2l1 knockdown on the expression of endoderm, mesoderm, and trophectoderm markers in mouse embryonic stem cells.
Wed Nov 15 00:00:00 EST 2017
Androgens Upregulate Endometrial Epithelial Progesterone Receptor Expression: Potential Implications for Endometriosis.
Reproductive sciences (Thousand Oaks, Calif.)
Babayev SN,Park CW,Keller PW,Carr BR,Word RA,Bukulmez O
32-2500 was used in Western Blotting to investigate whether androgens promote their endometrial effects via modulation of progesterone receptor expression.
Sun Oct 01 00:00:00 EDT 2017
Depletion of Tcf3 and Lef1 maintains mouse embryonic stem cell self-renewal.
Biology open
Ye S,Zhang T,Tong C,Zhou X,He K,Ban Q,Liu D,Ying QL
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Immunofluorescence
Sat Apr 15 00:00:00 EDT 2017
Counterbalancing anti-adhesive effects of Tenascin-C through fibronectin expression in endothelial cells.
Scientific reports
Radwanska A,Grall D,Schaub S,Divonne SBF,Ciais D,Rekima S,Rupp T,Sudaka A,Orend G,Van Obberghen-Schilling E
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Western Blot
Fri Oct 06 00:00:00 EDT 2017
Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells.
The Journal of biological chemistry
Huang Q,Merriman C,Zhang H,Fu D
32-2500 was used in Western Blotting to study the specific antibody binding to the extracellular surface of rat insulinoma INS-1E cells that stably express tagged ZnT8.
Fri Mar 10 00:00:00 EST 2017
Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.
Oncotarget
Weber H,Valbuena JR,Barbhuiya MA,Stein S,Kunkel H,García P,Bizama C,Riquelme I,Espinoza JA,Kurtz SE,Tyner JW,Calderon JF,Corvalán AH,Grez M,Pandey A,Leal-Rojas P,Roa JC
32-2500 was used in Western Blotting to screen 130 small molecules systematically, for antitumoural activity, specifically gallbladder cancer inhibition.
Tue Apr 18 00:00:00 EDT 2017
Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells.
The Journal of biological chemistry
Schauwecker SM,Kim JJ,Licht JD,Clevenger CV
322500 was used in western blot to determine the molecular mechanisms that enable JAK2/signal transducer and activator of transcription 5 to access promoters of genes implicated in breast cancer pathogenesis
Fri Feb 10 00:00:00 EST 2017
Axial superresolution via multiangle TIRF microscopy with sequential imaging and photobleaching.
Proceedings of the National Academy of Sciences of the United States of America
Fu Y,Winter PW,Rojas R,Wang V,McAuliffe M,Patterson GH
32-2500 was used in Immunocytochemistry-immunoflourescence to report superresolution optical sectioning using a multiangle total internal reflection fluorescence microscope.
Tue Apr 19 00:00:00 EDT 2016
The mRNA-binding protein HuR promotes hypoxia-induced chemoresistance through posttranscriptional regulation of the proto-oncogene PIM1 in pancreatic cancer cells.
Oncogene
Blanco FF,Jimbo M,Wulfkuhle J,Gallagher I,Deng J,Enyenihi L,Meisner-Kober N,Londin E,Rigoutsos I,Sawicki JA,Risbud MV,Witkiewicz AK,McCue PA,Jiang W,Rui H,Yeo CJ,Petricoin E,Winter JM,Brody JR
32-2500 was used in western blot to investigate the molecular mechanism by which PIM1 overexpression protects against pancreatic ductal adenocarcinoma
Sun May 01 00:00:00 EDT 2016
The Conoid Associated Motor MyoH Is Indispensable for Toxoplasma gondii Entry and Exit from Host Cells.
PLoS pathogens
Graindorge A,Frénal K,Jacot D,Salamun J,Marq JB,Soldati-Favre D
32-2500 was used in western blot to characterize class XIV myosin H and its associated light chains
Fri Jan 01 00:00:00 EST 2016
The Conoid Associated Motor MyoH Is Indispensable for Toxoplasma gondii Entry and Exit from Host Cells.
PLoS pathogens
Graindorge A,Frénal K,Jacot D,Salamun J,Marq JB,Soldati-Favre D
32-2500 was used in western blot to characterize class XIV myosin H and its associated light chains
Fri Jan 01 00:00:00 EST 2016
HDAC6 Deacetylates HMGN2 to Regulate Stat5a Activity and Breast Cancer Growth.
Molecular cancer research : MCR
Medler TR,Craig JM,Fiorillo AA,Feeney YB,Harrell JC,Clevenger CV
32-2500 was used in Western Blotting to examine a novel mechanism by which HDAC6 activity promotes transcription of Stat5a target genes, and demonstrate the utility of HDAC6 inhibition for breast cancer therapy.
Sat Oct 01 00:00:00 EDT 2016
Wnt/β-catenin and LIF-Stat3 signaling pathways converge on Sp5 to promote mouse embryonic stem cell self-renewal.
Journal of cell science
Ye S,Zhang D,Cheng F,Wilson D,Mackay J,He K,Ban Q,Lv F,Huang S,Liu D,Ying QL
32-2500 was used in western blot to study embryonic cell self-renewal via Wnt beta-catenin and LIF-Stat3 signalling pathways funneling into Sp5
Fri Jan 15 00:00:00 EST 2016
Housekeeping proteins: How useful are they in skeletal muscle diabetes studies and muscle hypertrophy models?
Analytical biochemistry
Fortes MA,Marzuca-Nassr GN,Vitzel KF,da Justa Pinheiro CH,Newsholme P,Curi R
32-2500 was used in western blot to determine the role of housekeeping proteins and their use in muscle hypertrophy models and skeletal muscle diabetes studies
Fri Jul 01 00:00:00 EDT 2016
Identification of NEK3 Kinase Threonine 165 as a Novel Regulatory Phosphorylation Site That Modulates Focal Adhesion Remodeling Necessary for Breast Cancer Cell Migration.
The Journal of biological chemistry
Harrington KM,Clevenger CV
322500 was used in western blot to test if prolactin phosphorylates NEK3 to promote migration of breast cancer cells
Fri Oct 07 00:00:00 EDT 2016
A Positive Feed-forward Loop Associating EGR1 and PDGFA Promotes Proliferation and Self-renewal in Glioblastoma Stem Cells.
The Journal of biological chemistry
Sakakini N,Turchi L,Bergon A,Holota H,Rekima S,Lopez F,Paquis P,Almairac F,Fontaine D,Baeza-Kallee N,Van Obberghen-Schilling E,Junier MP,Chneiweiss H,Figarella-Branger D,Burel-Vandenbos F,Imbert J,Virolle T
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Western Blot
Fri May 13 00:00:00 EDT 2016
Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis.
Oncotarget
Blanco FF,Preet R,Aguado A,Vishwakarma V,Stevens LE,Vyas A,Padhye S,Xu L,Weir SJ,Anant S,Meisner-Kober N,Brody JR,Dixon DA
322500 was used in western blot to evaluate the effects of treating colorectal cancer cells with an HuR inhibitor
Tue Nov 08 00:00:00 EST 2016
Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis.
Oncotarget
Blanco FF,Preet R,Aguado A,Vishwakarma V,Stevens LE,Vyas A,Padhye S,Xu L,Weir SJ,Anant S,Meisner-Kober N,Brody JR,Dixon DA
322500 was used in western blot to evaluate the effects of treating colorectal cancer cells with an HuR inhibitor
Tue Nov 08 00:00:00 EST 2016
PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins.
The Journal of biological chemistry
Guerrera D,Shah J,Vasileva E,Sluysmans S,Méan I,Jond L,Poser I,Mann M,Hyman AA,Citi S
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Western Blot
Fri May 20 00:00:00 EDT 2016
Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation.
PloS one
Blair JA,Wang C,Hernandez D,Siedlak SL,Rodgers MS,Achar RK,Fahmy LM,Torres SL,Petersen RB,Zhu X,Casadesus G,Lee HG
32-2500 was used in Immunohistochemistry-immunofluorescence and Western blot to assess the impact of postmortem interval time on brain tissue preservation.
Mon Jul 25 00:00:00 EDT 2016
Individual Case Analysis of Postmortem Interval Time on Brain Tissue Preservation.
PloS one
Blair JA,Wang C,Hernandez D,Siedlak SL,Rodgers MS,Achar RK,Fahmy LM,Torres SL,Petersen RB,Zhu X,Casadesus G,Lee HG
32-2500 was used in Immunohistochemistry-immunofluorescence and Western blot to assess the impact of postmortem interval time on brain tissue preservation.
Mon Jul 25 00:00:00 EDT 2016
SASH1, a new potential link between smoking and atherosclerosis.
Atherosclerosis
Weidmann H,Touat-Hamici Z,Durand H,Mueller C,Chardonnet S,Pionneau C,Charlotte F,Janssen KP,Verdugo R,Cambien F,Blankenberg S,Tiret L,Zeller T,Ninio E
32-2500 was used in Western Blotting to study the function of SASH1 and establish a link between it's expression, smoking, endothelial cell function, and carotid atherosclerotic plaque formation.
Thu Oct 01 00:00:00 EDT 2015
Functional Interaction Between Na/K-ATPase and NMDA Receptor in Cerebellar Neurons.
Molecular neurobiology
Akkuratov EE,Lopacheva OM,Kruusmägi M,Lopachev AV,Shah ZA,Boldyrev AA,Liu L
32-2500 was used in western blot to study the relationship between Na/K-ATPase and NMDA receptor in cerebellar neurons
Tue Dec 01 00:00:00 EST 2015
The Gcn2 Regulator Yih1 Interacts with the Cyclin Dependent Kinase Cdc28 and Promotes Cell Cycle Progression through G2/M in Budding Yeast.
PloS one
Silva RC,Dautel M,Di Genova BM,Amberg DC,Castilho BA,Sattlegger E
32-2500 was used in immunocytochemistry to demonstrate that Yih1/IMPACT are involved in the cell cycle regulation.
Thu Apr 21 00:00:00 EDT 2016
Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells.
Oncotarget
Jimbo M,Blanco FF,Huang YH,Telonis AG,Screnci BA,Cosma GL,Alexeev V,Gonye GE,Yeo CJ,Sawicki JA,Winter JM,Brody JR
32-2500 was used in western blot to study impairment of malignant characteristics of pancreatic ductal adenocarcinoma cells by targeting the mRNA-binding protein HuR
Tue Sep 29 00:00:00 EDT 2015
Klf2 and Tfcp2l1, Two Wnt/β-Catenin Targets, Act Synergistically to Induce and Maintain Naive Pluripotency.
Stem cell reports
Qiu D,Ye S,Ruiz B,Zhou X,Liu D,Zhang Q,Ying QL
32-2500 was used in western blot to study how Wnt/β-catenin regulates embryonic stem cell fate.
Tue Sep 08 00:00:00 EDT 2015
Long-term disruption of maternal glucose homeostasis induced by prenatal glucocorticoid treatment correlates with miR-29 upregulation.
American journal of physiology. Endocrinology and metabolism
Gomes PR,Graciano MF,Pantaleão LC,Rennó AL,Rodrigues SC,Velloso LA,Latorraca MQ,Carpinelli AR,Anhê GF,Bordin S
32-2500 was used in Western Blotting to demonstrate that the use of DEX during pregnancy results in deleterious outcomes to the maternal metabolism, hallmarked by reduced insulin secretion and glucose intolerance.
Wed Jan 01 00:00:00 EST 2014
Progeny from irradiated colorectal cancer cells acquire an EMT-like phenotype and activate Wnt/β-catenin pathway.
Journal of cellular biochemistry
Bastos LG,de Marcondes PG,de-Freitas-Junior JC,Leve F,Mencalha AL,de Souza WF,de Araujo WM,Tanaka MN,Abdelhay ES,Morgado-Díaz JA
32-2500 was used in western blot to study the effect of radiation on the progeny of colorectal cancer cells
Mon Dec 01 00:00:00 EST 2014
Intracellular trafficking of AIP56, an NF-κB-cleaving toxin from Photobacterium damselae subsp. piscicida.
Infection and immunity
Pereira LM,Pinto RD,Silva DS,Moreira AR,Beitzinger C,Oliveira P,Sampaio P,Benz R,Azevedo JE,dos Santos NM,do Vale A
32-2500 was used in western blot to investigate the intracellular trafficking of an NF-kappaB-cleaving toxin from Photobacterium damselae subsp. piscicida
Mon Dec 01 00:00:00 EST 2014
Changes in substance P and NK1 receptor immunohistochemistry following human spinal cord injury.
Spinal cord
Leonard AV,Manavis J,Blumbergs PC,Vink R
32-2500 was used in immunohistochemistry - paraffin section to study the immunohistochemical expression of substance P, NK1 and claudin-5 in traumatic spinal cord injury tissue.
Wed Jan 01 00:00:00 EST 2014
PLEKHA7 modulates epithelial tight junction barrier function.
Tissue barriers
Paschoud S,Jond L,Guerrera D,Citi S
32-2500 was used in immunocytochemistry and western blot to test whether PLEKHA7 protein modulates epithelial tight junction barrier function
Wed Jan 01 00:00:00 EST 2014
PLEKHA7 modulates epithelial tight junction barrier function.
Tissue barriers
Paschoud S,Jond L,Guerrera D,Citi S
32-2500 was used in immunocytochemistry and western blot to test whether PLEKHA7 protein modulates epithelial tight junction barrier function
Wed Jan 01 00:00:00 EST 2014
PLEKHA7 modulates epithelial tight junction barrier function.
Tissue barriers
Paschoud S,Jond L,Guerrera D,Citi S
32-2500 was used in immunocytochemistry and western blot to test whether PLEKHA7 protein modulates epithelial tight junction barrier function
Wed Jan 01 00:00:00 EST 2014
Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy.
eLife
Yamano K,Fogel AI,Wang C,van der Bliek AM,Youle RJ
32-2500 was used in immunocytochemistry and western blot to analyze the governing of autophagosome biogenesis during mitophagy via mitochondrial Rab GAPs
Tue Feb 25 00:00:00 EST 2014
Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1.
The EMBO journal
Ye S,Li P,Tong C,Ying QL
Wed Oct 02 00:00:00 EDT 2013
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria.
Autophagy
Jin SM,Youle RJ
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Western Blot
Fri Nov 01 00:00:00 EDT 2013
PINK1 is degraded through the N-end rule pathway.
Autophagy
Yamano K,Youle RJ
32-2500 was used in western blot to elucidate how PINK1 tags damaged mitochondria for autophagic elimination.
Fri Nov 01 00:00:00 EDT 2013
PINK1 is degraded through the N-end rule pathway.
Autophagy
Yamano K,Youle RJ
32-2500 was used in western blot to elucidate how PINK1 tags damaged mitochondria for autophagic elimination.
Fri Nov 01 00:00:00 EDT 2013
H. pylori-encoded CagA disrupts tight junctions and induces invasiveness of AGS gastric carcinoma cells via Cdx2-dependent targeting of Claudin-2.
Cellular immunology
Song X,Chen HX,Wang XY,Deng XY,Xi YX,He Q,Peng TL,Chen J,Chen W,Wong BC,Chen MH
32-2500 was used in western blot to show that H. pylori-encoded CagA disrupts tight junctions and induces invasiveness of AGS gastric carcinoma cells via Cdx2-dependent targeting of Claudin-2.
Wed Feb 05 00:00:00 EST 2014
Claudin-3 overexpression increases the malignant potential of colorectal cancer cells: roles of ERK1/2 and PI3K-Akt as modulators of EGFR signaling.
PloS one
de Souza WF,Fortunato-Miranda N,Robbs BK,de Araujo WM,de-Freitas-Junior JC,Bastos LG,Viola JP,Morgado-Díaz JA
32-2500 was used in western blot to show that claudin-3 overexpression, regulated by EGF-activated ERK/2 and PI3K-Akt pathways, promotes the malignant potential of colorectal cancer cells.
Sun Jun 15 00:00:00 EDT 2014
Modulation of β-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal.
Nature communications
Kim H,Wu J,Ye S,Tai CI,Zhou X,Yan H,Li P,Pera M,Ying QL
32-2500 was used in Western Blotting to study the role of Wnt/Β-catenin signalling in mouse epiblast stem cell self-renewal.
Tue Apr 01 00:00:00 EDT 2014
Modulation of β-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal.
Nature communications
Kim H,Wu J,Ye S,Tai CI,Zhou X,Yan H,Li P,Pera M,Ying QL
32-2500 was used in Western Blotting to study the role of Wnt/Β-catenin signalling in mouse epiblast stem cell self-renewal.
Tue Apr 01 00:00:00 EDT 2014
Resolution doubling in live, multicellular organisms via multifocal structured illumination microscopy.
Nature methods
York AG,Parekh SH,Dalle Nogare D,Fischer RS,Temprine K,Mione M,Chitnis AB,Combs CA,Shroff H
32-2500 was used in Immunocytochemistry-immunoflourescence to demonstrate three-dimensional super-resolution in live multicellular organisms using structured illumination microscopy.
Sun May 13 00:00:00 EDT 2012
Effects of proinflammatory cytokines on the claudin-19 rich tight junctions of human retinal pigment epithelium.
Investigative ophthalmology & visual science
Peng S,Gan G,Rao VS,Adelman RA,Rizzolo LJ
Fri Jul 27 00:00:00 EDT 2012
Effects of proinflammatory cytokines on the claudin-19 rich tight junctions of human retinal pigment epithelium.
Investigative ophthalmology & visual science
Peng S,Gan G,Rao VS,Adelman RA,Rizzolo LJ
Fri Jul 27 00:00:00 EDT 2012
Biomechanics of meniscus cells: regional variation and comparison to articular chondrocytes and ligament cells.
Biomechanics and modeling in mechanobiology
Sanchez-Adams J,Athanasiou KA
Sat Sep 01 00:00:00 EDT 2012
Biomechanics of meniscus cells: regional variation and comparison to articular chondrocytes and ligament cells.
Biomechanics and modeling in mechanobiology
Sanchez-Adams J,Athanasiou KA
Sat Sep 01 00:00:00 EDT 2012
A gatekeeper residue for NEDD8-activating enzyme inhibition by MLN4924.
Cell reports
Toth JI,Yang L,Dahl R,Petroski MD
32-2500 was used in western blot to elucidate resistance to MLN4924.
Thu Apr 19 00:00:00 EDT 2012
Cytotoxic effects of iron oxide nanoparticles and implications for safety in cell labelling.
Biomaterials
Soenen SJ,Himmelreich U,Nuytten N,De Cuyper M
32-2500 was used in immunocytochemistry to report the cytotoxicity of various nanoparticles
Sat Jan 01 00:00:00 EST 2011
Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium.
The Journal of cell biology
Gerbe F,van Es JH,Makrini L,Brulin B,Mellitzer G,Robine S,Romagnolo B,Shroyer NF,Bourgaux JF,Pignodel C,Clevers H,Jay P
32-2500 was used in immunohistochemistry - paraffin section to characterize intestinal tuft cells
Mon Mar 07 00:00:00 EST 2011
How to assess cytotoxicity of (iron oxide-based) nanoparticles: a technical note using cationic magnetoliposomes.
Contrast media & molecular imaging
Soenen SJ,De Cuyper M
32-2500 was used in Immunocytochemistry-immunoflourescence to develop a detailed guide to assess the cytotoxicity of iron oxide-based nanoparticles.
Wed Nov 02 00:00:00 EDT 2011
Cingulin and paracingulin show similar dynamic behaviour, but are recruited independently to junctions.
Molecular membrane biology
Paschoud S,Yu D,Pulimeno P,Jond L,Turner JR,Citi S
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Immunofluorescence
Tue Feb 01 00:00:00 EST 2011
The nuclear matrix shell proteome of human epidermis.
Journal of dermatological science
Warters RL,Cassidy PB,Sunseri JA,Parsawar K,Zhuplatov SB,Kramer GF,Leachman SA
32-2500 was used in western blot to use the nuclear matrix fraction to identify melanoma biomarkers
Sat May 01 00:00:00 EDT 2010
Cyclophilin B as a co-regulator of prolactin-induced gene expression and function in breast cancer cells.
Journal of molecular endocrinology
Fang F,Zheng J,Galbaugh TL,Fiorillo AA,Hjort EE,Zeng X,Clevenger CV
32-2500 was used in western blot to assess the effect of cyclophilin B knockdown on prolactin signaling in breast cancer cells
Tue Jun 01 00:00:00 EDT 2010
Expression of cyclophilin B is associated with malignant progression and regulation of genes implicated in the pathogenesis of breast cancer.
The American journal of pathology
Fang F,Flegler AJ,Du P,Lin S,Clevenger CV
Thu Jan 01 00:00:00 EST 2009
Expression of cyclophilin B is associated with malignant progression and regulation of genes implicated in the pathogenesis of breast cancer.
The American journal of pathology
Fang F,Flegler AJ,Du P,Lin S,Clevenger CV
Thu Jan 01 00:00:00 EST 2009
Differential gene expression in primary human skin keratinocytes and fibroblasts in response to ionizing radiation.
Radiation research
Warters RL,Packard AT,Kramer GF,Gaffney DK,Moos PJ
32-2500 was used in Western Blotting to confirm changes in the expression of p53 target genes to indicate the magnitude of cell responses to ionising radiation.
Wed Jul 01 00:00:00 EDT 2009
Control of chromosome stability by the beta-TrCP-REST-Mad2 axis.
Nature
Guardavaccaro D,Frescas D,Dorrello NV,Peschiaroli A,Multani AS,Cardozo T,Lasorella A,Iavarone A,Chang S,Hernando E,Pagano M
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Immunofluorescence
Thu Mar 20 00:00:00 EDT 2008
Control of chromosome stability by the beta-TrCP-REST-Mad2 axis.
Nature
Guardavaccaro D,Frescas D,Dorrello NV,Peschiaroli A,Multani AS,Cardozo T,Lasorella A,Iavarone A,Chang S,Hernando E,Pagano M
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Immunofluorescence
Thu Mar 20 00:00:00 EDT 2008
KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state.
Cell cycle (Georgetown, Tex.)
Frescas D,Guardavaccaro D,Kuchay SM,Kato H,Poleshko A,Basrur V,Elenitoba-Johnson KS,Katz RA,Pagano M
32-2500 was used in immunocytochemistry to discuss the role of KDM2A in cancer development
Sat Nov 15 00:00:00 EST 2008
KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state.
Cell cycle (Georgetown, Tex.)
Frescas D,Guardavaccaro D,Kuchay SM,Kato H,Poleshko A,Basrur V,Elenitoba-Johnson KS,Katz RA,Pagano M
32-2500 was used in immunocytochemistry to discuss the role of KDM2A in cancer development
Sat Nov 15 00:00:00 EST 2008
KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state.
Cell cycle (Georgetown, Tex.)
Frescas D,Guardavaccaro D,Kuchay SM,Kato H,Poleshko A,Basrur V,Elenitoba-Johnson KS,Katz RA,Pagano M
32-2500 was used in immunocytochemistry to discuss the role of KDM2A in cancer development
Sat Nov 15 00:00:00 EST 2008
ZO-1 is required for protein kinase C gamma-driven disassembly of connexin 43.
Cellular signalling
Akoyev V,Takemoto DJ
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Western Blot
Tue May 01 00:00:00 EDT 2007
Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling.
The Journal of biological chemistry
Li MH,Jang JH,Na HK,Cha YN,Surh YJ
32-2500 was used in Western Blotting to conclude that CO produced by HO-1 rescues PC12 cells from nitrosative stress through induction of GCLC, which is mediated by activation of phosphatidylinositol 3-kinase/Akt and subsequently Nrf2 signaling.
Fri Sep 28 00:00:00 EDT 2007
Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling.
The Journal of biological chemistry
Li MH,Jang JH,Na HK,Cha YN,Surh YJ
32-2500 was used in Western Blotting to conclude that CO produced by HO-1 rescues PC12 cells from nitrosative stress through induction of GCLC, which is mediated by activation of phosphatidylinositol 3-kinase/Akt and subsequently Nrf2 signaling.
Fri Sep 28 00:00:00 EDT 2007
Differentiation of mouse embryonic stem cells after RNA interference-mediated silencing of OCT4 and Nanog.
Stem cells (Dayton, Ohio)
Hough SR,Clements I,Welch PJ,Wiederholt KA
Published figure using alpha Tubulin monoclonal antibody (Product # 32-2500) in Western Blot
Thu Jun 01 00:00:00 EDT 2006
Caspase-7 gene disruption reveals an involvement of the enzyme during the early stages of apoptosis.
The Journal of biological chemistry
Korfali N,Ruchaud S,Loegering D,Bernard D,Dingwall C,Kaufmann SH,Earnshaw WC
Fri Jan 09 00:00:00 EST 2004
Gap junction-microtubule associations in rat alveolar epithelial cells.
American journal of physiology. Lung cellular and molecular physiology
Guo Y,Martinez-Williams C,Rannels DE
Mon Dec 01 00:00:00 EST 2003
Gap junction-microtubule associations in rat alveolar epithelial cells.
American journal of physiology. Lung cellular and molecular physiology
Guo Y,Martinez-Williams C,Rannels DE
Mon Dec 01 00:00:00 EST 2003
A-kinase-anchoring protein AKAP95 is targeted to the nuclear matrix and associates with p68 RNA helicase.
The Journal of biological chemistry
Akileswaran L,Taraska JW,Sayer JA,Gettemy JM,Coghlan VM
32-2500 was used in immunocytochemistry to test if AKAP95 contains specific signals for targeting it to the subnuclear compartment and for interaction with other proteins
Fri May 18 00:00:00 EDT 2001
Inhibition of endothelial cell migration, intercellular communication, and vascular tube formation by thromboxane A(2).
The Journal of biological chemistry
Ashton AW,Yokota R,John G,Zhao S,Suadicani SO,Spray DC,Ware JA
32-2500 was used in immunocytochemistry to test if eicosanoid thromboxane A(2) alters endothelial migration and tube formation
Fri Dec 10 00:00:00 EST 1999
