Product References
The dual role of boron in vitro neurotoxication of glioblastoma cells via SEMA3F/NRP2 and ferroptosis signaling pathways.
Environmental toxicology
Kar F,Hacioğlu C,Kaçar S
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Sun Jan 01 00:00:00 EST 2023
The dual role of boron in vitro neurotoxication of glioblastoma cells via SEMA3F/NRP2 and ferroptosis signaling pathways.
Environmental toxicology
Kar F,Hacioğlu C,Kaçar S
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Sun Jan 01 00:00:00 EST 2023
The Sde phosphoribosyl-linked ubiquitin transferases protect the Legionella pneumophila vacuole from degradation by the host.
Proceedings of the National Academy of Sciences of the United States of America
Kim S,Isberg RR
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Tue Aug 15 00:00:00 EDT 2023
CB1R blockade unmasks TRPV1-mediated contextual fear generalization in female, but not male rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Huckleberry KA,Calitri R,Li AJ,Mejdell M,Singh A,Bhutani V,Laine MA,Nastase AS,Morena M,Hill MN,Shansky RM
PA1-183 was used in Western Blotting to support a model in which sexual dimorphism in vHip-BLA circuitry promotes a female-specific dependence on CB1Rs for context processing that is sensitive to TRPV1-mediated disruption when CB1Rs are blocked.
Fri Sep 01 00:00:00 EDT 2023
Adapted clustering method for generic analysis of histological fibrosis staining as an open source tool.
Scientific reports
Remes A,Noormalal M,Schmiedel N,Frey N,Frank D,Müller OJ,Graf M
PA1-183 was used in Western Blot to demonstrate that FibroSoft can identify fibrosis in diseased myocardium and the obtained results are user-independent.
Thu Mar 16 00:00:00 EDT 2023
The miRNA Content of Bone Marrow-Derived Extracellular Vesicles Contributes to Protein Pathway Alterations Involved in Ionising Radiation-Induced Bystander Responses.
International journal of molecular sciences
Csordás IB,Rutten EA,Szatmári T,Subedi P,Cruz-Garcia L,Kis D,Jezsó B,Toerne CV,Forgács M,Sáfrány G,Tapio S,Badie C,Lumniczky K
PA1-183 was used in Western Blotting to characterise proteomic changes in directly irradiated and EV-treated BM cells, identified processes transmitted in a bystander manner and suggested miRNA and protein candidates potentially involved in the regulation of these bystander processes.
Thu May 11 00:00:00 EDT 2023
Therapeutic effects of a standardized-flavonoid Diospyros kaki L.f. leaf extract on transient focal cerebral ischemia-induced brain injury in mice.
Journal of natural medicines
Nguyen LTT,Le XT,Pham HNT,Van Nguyen T,Nguyen PT,Van Thi Pham A,Nguyen TBT,Matsumoto K
PA1-183 was used in Western Blotting to indicate that DK exerts neuroprotective and therapeutic activity against transient focal cerebral ischemia-induced injury probably by suppressing oxidative stress, apoptotic process, and mechanisms impairing blood-brain barrier integrity in the brain.
Thu Jun 01 00:00:00 EDT 2023
Principles of mitoribosomal small subunit assembly in eukaryotes.
Nature
Harper NJ,Burnside C,Klinge S
PA1-183 was used in Western Blotting to determine nine structures of native yeast and human mitoribosomal small subunit assembly intermediates, illuminating the mechanistic basis for how GTPases are used to control early steps of decoding centre formation, how initial rRNA folding and processing events are mediated, and how mitoribosomal proteins have active roles during assembly.
Wed Feb 01 00:00:00 EST 2023
KISS1R and ANKRD31 Cooperate to Enhance Leydig Cell Gene Expression via the Cytoskeletal-Nucleoskeletal Pathway.
Frontiers in cell and developmental biology
Ricci G,Guillou F,Catizone A,Mele VG,Moggio M,Chioccarelli T,Diano N,Meccariello R,Pierantoni R,Fasano S,Cobellis G,Chianese R,Manfrevola F
PA1-183 was used in Western Blotting to highlight a novel role for the Kisspeptin-10 in the induction of the cytoskeletal-nucleoskeletal route, downstream a physical interaction between KISS1 receptor and ANKRD31, with gene expression activation as final effect, in Leydig cells.
Sat Jul 16 00:00:00 EDT 2022
DNMT1-Mediated DNA Methylation Targets CDKN2B to Promote the Repair of Retinal Ganglion Cells in Streptozotocin-Induced Mongolian Gerbils during Diabetic Retinopathy.
Computational and mathematical methods in medicine
Wang X,Zhang J,Liao Y,Jin Y,Yu X,Li H,Yang Q,Li X,Chen R,Wu D,Zhu H
PA1-183 was used in Western Blot to explore the role of DNA cytosine-5-methyltransferase 1 (DNMT1) in the development of early diabetic retinopathy and its potential underlying mechanism.
Mon Mar 28 00:00:00 EDT 2022
Exploring Amodiaquine's Repurposing Potential in Breast Cancer Treatment-Assessment of In-Vitro Efficacy & Mechanism of Action.
International journal of molecular sciences
Parvathaneni V,Chilamakuri R,Kulkarni NS,Baig NF,Agarwal S,Gupta V
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Wed Sep 28 00:00:00 EDT 2022
Exploring Amodiaquine's Repurposing Potential in Breast Cancer Treatment-Assessment of In-Vitro Efficacy & Mechanism of Action.
International journal of molecular sciences
Parvathaneni V,Chilamakuri R,Kulkarni NS,Baig NF,Agarwal S,Gupta V
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Wed Sep 28 00:00:00 EDT 2022
Hemizygous Granzyme A Mice Expressing the hSOD1G93A Transgene Show Slightly Extended Lifespan.
International journal of molecular sciences
Moreno-Martinez L,Santiago L,de la Torre M,Calvo AC,Pardo J,Osta R
PA1-183 was used in Western Blotting to indicate for the first time that reduced levels, but not the absence, of gzmA could slightly ameliorate the disease progression in this animal model.
Fri Nov 04 00:00:00 EDT 2022
VGLUT3 Ablation Differentially Modulates Glutamate Receptor Densities in Mouse Brain.
eNeuro
Ibrahim KS,El Mestikawy S,Abd-Elrahman KS,Ferguson SSG
PA1-183 was used in Western Blotting to explore how VGLUT3 deletion influences total and cell surface expression of different ionotropic and metabotropic glutamate receptors.
Wed May 11 00:00:00 EDT 2022
Organochlorine pesticides induce epithelial as well as inflammatory mediators following exposure to human ovarian surface epithelial cells: An in vitro study.
Journal of biochemical and molecular toxicology
Shah HK,Banerjee BD,Thakur GK,Guleria K
PA1-183 was used in Immunocytochemistry, Immunoprecipitation, Western Blot to investigate the impact of dichlorodiphenyldichloroethylene (DDE), endosulfan, and heptachlor exposure on epithelial cadherin (E-cadherin) and proinflammatory mediators in human ovary surface epithelial (HOSE) cells.
Tue Nov 01 00:00:00 EDT 2022
Vitamin D modulates hepatic microRNAs and mitigates tamoxifen-induced steatohepatitis in female rats.
Fundamental & clinical pharmacology
Abd El-Haleim EA,Sallam NA
PA1-183 was used in Western Blotting to show that combination therapy of VD and TAM has complementary benefits in terms of safety and not only efficacy and should be further investigated clinically.
Fri Apr 01 00:00:00 EDT 2022
Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation.
Developmental cell
Vukušić K,Ponjavić I,Buđa R,Risteski P,Tolić IM
PA1-183 was used in Western Blotting to discover that the force-generating mechanism of spindle elongation consists of EG5/kinesin-5 together with the PRC1-dependent motor KIF4A/kinesin-4, with contribution from kinesin-6 and kinesin-8.
Mon May 03 00:00:00 EDT 2021
microRNA-196b promotes esophageal squamous cell carcinogenesis and chemoradioresistance by inhibiting EPHA7, thereby restoring EPHA2 activity.
American journal of cancer research
Tan X,Ren S,Fu MZ,Ren S,Yang C,Wu X,Chen T,Latham PS,Meltzer SJ,Fu SW
PA1-183 was used in Western Blot to suggest that miR-196b is a strong candidate molecular target for EC treatment.
Sat Aug 07 00:00:00 EDT 2021
IL-9 Abrogates the Metastatic Potential of Breast Cancer by Controlling Extracellular Matrix Remodeling and Cellular Contractility.
Journal of immunology (Baltimore, Md. : 1950)
Das S,Surve V,Marathe S,Wad S,Karulkar A,Srinivasan S,Dwivedi A,Barthel SR,Purwar R
PA1-183 was used in Western Blotting to support that IL-9 inhibits the metastatic potential of breast and cervical cancer cells by controlling extracellular matrix remodeling and cellular contractility.
Tue Jun 01 00:00:00 EDT 2021
Surface activation with oxygen plasma promotes osteogenesis with enhanced extracellular matrix formation in three-dimensional microporous scaffolds.
Journal of biomedical materials research. Part A
Yamada S,Yassin MA,Weigel T,Schmitz T,Hansmann J,Mustafa K
PA1-183 was used in Immunocytochemistry to show the utility of plasma surface activation for polymeric scaffolds in bone tissue engineering.
Wed Sep 01 00:00:00 EDT 2021
Downregulation of miR-375 contributes to ERBB2-mediated VEGFA overexpression in esophageal cancer.
Journal of Cancer
Ren S,Tan X,Fu MZ,Ren S,Wu X,Chen T,Latham PS,Lin P,Man YG,Fu SW
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Fri Nov 05 00:00:00 EDT 2021
Downregulation of miR-375 contributes to ERBB2-mediated VEGFA overexpression in esophageal cancer.
Journal of Cancer
Ren S,Tan X,Fu MZ,Ren S,Wu X,Chen T,Latham PS,Lin P,Man YG,Fu SW
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Fri Nov 05 00:00:00 EDT 2021
Bcl2l10 induces metabolic alterations in ovarian cancer cells by regulating the TCA cycle enzymes SDHD and IDH1.
Oncology reports
Lee SY,Kwon J,Lee KA
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Thu Apr 01 00:00:00 EDT 2021
Bcl2l10 induces metabolic alterations in ovarian cancer cells by regulating the TCA cycle enzymes SDHD and IDH1.
Oncology reports
Lee SY,Kwon J,Lee KA
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Thu Apr 01 00:00:00 EDT 2021
Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging.
International journal of molecular sciences
Yang MH,Chen YA,Tu SC,Chi PL,Chuang KP,Chang CC,Lee CH,Chen YL,Lee CH,Yuan CH,Tyan YC
PA1-183 was used in Western Blot to explore the effects of glycine-N-methyltransferase on neurons in a mouse model.
Tue Mar 23 00:00:00 EDT 2021
Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging.
International journal of molecular sciences
Yang MH,Chen YA,Tu SC,Chi PL,Chuang KP,Chang CC,Lee CH,Chen YL,Lee CH,Yuan CH,Tyan YC
PA1-183 was used in Western Blot to explore the effects of glycine-N-methyltransferase on neurons in a mouse model.
Tue Mar 23 00:00:00 EDT 2021
Coumestrol mitigates retinal cell inflammation, apoptosis, and oxidative stress in a rat model of diabetic retinopathy via activation of SIRT1.
Aging
Xu Y,Zhang Y,Liang H,Liu X
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Mon Feb 01 00:00:00 EST 2021
Impact of the molar activity and PSMA expression level on [18F]AlF-PSMA-11 uptake in prostate cancer.
Scientific reports
Piron S,Verhoeven J,De Coster E,Descamps B,Kersemans K,Pieters L,Vral A,Vanhove C,De Vos F
PA1-183 was used in Western Blotting to evaluate prostate specific membrane antigen (PSMA) as a valuable target for expression-based imaging applications and to determine changes in target binding in function of varying apparent molar activities (MAapp) of [18F]AlF-PSMA-11.
Fri Nov 19 00:00:00 EST 2021
Impact of the molar activity and PSMA expression level on [18F]AlF-PSMA-11 uptake in prostate cancer.
Scientific reports
Piron S,Verhoeven J,De Coster E,Descamps B,Kersemans K,Pieters L,Vral A,Vanhove C,De Vos F
PA1-183 was used in Western Blotting to evaluate prostate specific membrane antigen (PSMA) as a valuable target for expression-based imaging applications and to determine changes in target binding in function of varying apparent molar activities (MAapp) of [18F]AlF-PSMA-11.
Fri Nov 19 00:00:00 EST 2021
Social isolation-related depression accelerates ethanol intake via microglia-derived neuroinflammation.
Science advances
Lee JS,Lee SB,Kim DW,Shin N,Jeong SJ,Yang CH,Son CG
PA1-183 was used in Western Blot to demonstrate that microglial activation is a key mediator in the vicious cycle between depression and alcohol consumption.
Fri Nov 05 00:00:00 EDT 2021
Social isolation-related depression accelerates ethanol intake via microglia-derived neuroinflammation.
Science advances
Lee JS,Lee SB,Kim DW,Shin N,Jeong SJ,Yang CH,Son CG
PA1-183 was used in Western Blot to demonstrate that microglial activation is a key mediator in the vicious cycle between depression and alcohol consumption.
Fri Nov 05 00:00:00 EDT 2021
Quantitative Proteomic Approach Reveals Altered Metabolic Pathways in Response to the Inhibition of Lysine Deacetylases in A549 Cells under Normoxia and Hypoxia.
International journal of molecular sciences
Martín-Bernabé A,Tarragó-Celada J,Cunin V,Michelland S,Cortés R,Poignant J,Boyault C,Rachidi W,Bourgoin-Voillard S,Cascante M,Seve M
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Thu Mar 25 00:00:00 EDT 2021
Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production.
Frontiers in pharmacology
El-Sherbiny M,Atef H,Eladl MA,Mohamed AS,El-Shafey M,Ali HS,Zaitone SA,Alomar SY,Alqahtani SAM,Aloyouni SY,Attia MA
PA1-183 was used in Western Blot to examine the dose-dependent lung injury produced by leflunomide in healthy mice.
Tue May 18 00:00:00 EDT 2021
Regulation of tumor immune suppression and cancer cell survival by CXCL1/2 elevation in glioblastoma multiforme.
Science advances
Hu J,Zhao Q,Kong LY,Wang J,Yan J,Xia X,Jia Z,Heimberger AB,Li S
PA1-183 was used in Flow Cytometry,ELISA to show that elevation of CXCL1 or CXCL2 facilitated myeloid cell migration and simultaneously disrupted CD8+ T cell accumulation at tumor sites, causing accelerated tumor progression.
Fri Jan 01 00:00:00 EST 2021
Regulation of tumor immune suppression and cancer cell survival by CXCL1/2 elevation in glioblastoma multiforme.
Science advances
Hu J,Zhao Q,Kong LY,Wang J,Yan J,Xia X,Jia Z,Heimberger AB,Li S
PA1-183 was used in Flow Cytometry,ELISA to show that elevation of CXCL1 or CXCL2 facilitated myeloid cell migration and simultaneously disrupted CD8+ T cell accumulation at tumor sites, causing accelerated tumor progression.
Fri Jan 01 00:00:00 EST 2021
Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity.
Frontiers in immunology
Chowdhury D,Gardner JC,Satpati A,Nookala S,Mukundan S,Porollo A,Landero Figueroa JA,Subramanian Vignesh K
PA1-183 was used in Western Blotting to identify that the caspase-11 inflammasome in mouse and human macrophages (Mφ) is negatively controlled by the zinc (Zn2+) regulating protein, metallothionein 3 (MT3).
Mon Feb 07 00:00:00 EST 2022
DAPK3 participates in the mRNA processing of immediate early genes in chronic lymphocytic leukaemia.
Molecular oncology
Thomas F,Holmes KB,Kreuz S,Hillmen P,Lefevre PF
PA1-183 was used in Western Blotting to show that the DAPK inhibitor does not repress transcription itself but impacts on mRNA processing and has a broader anti-tumour effect than ibrutinib, by repressing both anti-IgM- and CD40L-dependent activation.
Mon Jun 01 00:00:00 EDT 2020
DAPK3 participates in the mRNA processing of immediate early genes in chronic lymphocytic leukaemia.
Molecular oncology
Thomas F,Holmes KB,Kreuz S,Hillmen P,Lefevre PF
PA1-183 was used in Western Blotting to show that the DAPK inhibitor does not repress transcription itself but impacts on mRNA processing and has a broader anti-tumour effect than ibrutinib, by repressing both anti-IgM- and CD40L-dependent activation.
Mon Jun 01 00:00:00 EDT 2020
Metformin Protects From Rotenone-Induced Nigrostriatal Neuronal Death in Adult Mice by Activating AMPK-FOXO3 Signaling and Mitigation of Angiogenesis.
Frontiers in molecular neuroscience
El-Ghaiesh SH,Bahr HI,Ibrahiem AT,Ghorab D,Alomar SY,Farag NE,Zaitone SA
PA1-183 was used in Western Blotting to investigate the neuroprotective effect of MTF in a mouse model of rotenone-prompted PD with a highlight on its influence on the AMPK/forkhead box transcription factor O3 (FOXO3) pathway and striatal angiogenesis.
Mon Sep 28 00:00:00 EDT 2020
Bcl2l10 mediates the proliferation, invasion and migration of ovarian cancer cells.
International journal of oncology
Lee SY,Kwon J,Woo JH,Kim KH,Lee KA
PA1-183 was used in Western Blotting to investigate the regulatory role of Bcl2l10 in A2780 and SKOV3 human ovarian cancer cells.
Sat Feb 01 00:00:00 EST 2020
Silymarin, boswellic acid and curcumin enriched dietetic formulation reduces the growth of inherited intestinal polyps in an animal model.
World journal of gastroenterology
Girardi B,Pricci M,Giorgio F,Piazzolla M,Iannone A,Losurdo G,Principi M,Barone M,Ierardi E,Di Leo A
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Tue Apr 14 00:00:00 EDT 2020
Silymarin, boswellic acid and curcumin enriched dietetic formulation reduces the growth of inherited intestinal polyps in an animal model.
World journal of gastroenterology
Girardi B,Pricci M,Giorgio F,Piazzolla M,Iannone A,Losurdo G,Principi M,Barone M,Ierardi E,Di Leo A
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Tue Apr 14 00:00:00 EDT 2020
miR-4463 regulates aromatase expression and activity for 17β-estradiol synthesis in response to follicle-stimulating hormone.
Clinical and experimental reproductive medicine
Lee SY,Kang YJ,Kwon J,Nishi Y,Yanase T,Lee KA,Koong MK
PA1-183 was used in Western Blotting to investigate microRNAs related to follicle-stimulating hormone responsiveness using miRNA microarrays and to identify their target genes to determine the molecular regulatory pathways involved in FSH signaling in KGN cells.
Tue Sep 01 00:00:00 EDT 2020
miR-4463 regulates aromatase expression and activity for 17β-estradiol synthesis in response to follicle-stimulating hormone.
Clinical and experimental reproductive medicine
Lee SY,Kang YJ,Kwon J,Nishi Y,Yanase T,Lee KA,Koong MK
PA1-183 was used in Western Blotting to investigate microRNAs related to follicle-stimulating hormone responsiveness using miRNA microarrays and to identify their target genes to determine the molecular regulatory pathways involved in FSH signaling in KGN cells.
Tue Sep 01 00:00:00 EDT 2020
Actively Targeted Nanodelivery of Echinomycin Induces Autophagy-Mediated Death in Chemoresistant Pancreatic Cancer In Vivo.
Cancers
Thomas A,Samykutty A,Gomez-Gutierrez JG,Yin W,Egger ME,McNally M,Chuong P,MacCuaig WM,Albeituni S,Zeiderman M,Li M,Edil BH,Grizzle WE,McMasters KM,McNally LR
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Fri Aug 14 00:00:00 EDT 2020
Actively Targeted Nanodelivery of Echinomycin Induces Autophagy-Mediated Death in Chemoresistant Pancreatic Cancer In Vivo.
Cancers
Thomas A,Samykutty A,Gomez-Gutierrez JG,Yin W,Egger ME,McNally M,Chuong P,MacCuaig WM,Albeituni S,Zeiderman M,Li M,Edil BH,Grizzle WE,McMasters KM,McNally LR
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Fri Aug 14 00:00:00 EDT 2020
Effects of suppressing bioavailability of insulin-like growth factor on age-associated intervertebral disc degeneration.
JOR spine
Kritschil R,Zhang Z,Lei C,Zhong J,Dong Q,Lee J,Conover CA,Sowa G,Vallejo AN,Vo N
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Tue Dec 01 00:00:00 EST 2020
Effects of suppressing bioavailability of insulin-like growth factor on age-associated intervertebral disc degeneration.
JOR spine
Kritschil R,Zhang Z,Lei C,Zhong J,Dong Q,Lee J,Conover CA,Sowa G,Vallejo AN,Vo N
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Tue Dec 01 00:00:00 EST 2020
Neuroprotective Fragment C of Tetanus Toxin Modulates IL-6 in an ALS Mouse Model.
Toxins
Moreno-Martinez L,de la Torre M,Muñoz MJ,Zaragoza P,Aguilera J,Calvo AC,Osta R
PA1-183 was used in Western Blotting to assess the effect of tetanus toxin C-terminal fragment (TTC) on the regulation of inflammatory mediators to elucidate its potential role in modulating inflammation occurring in amyotrophic lateral sclerosis (ALS).
Sun May 17 00:00:00 EDT 2020
Neuroprotective Fragment C of Tetanus Toxin Modulates IL-6 in an ALS Mouse Model.
Toxins
Moreno-Martinez L,de la Torre M,Muñoz MJ,Zaragoza P,Aguilera J,Calvo AC,Osta R
PA1-183 was used in Western Blotting to assess the effect of tetanus toxin C-terminal fragment (TTC) on the regulation of inflammatory mediators to elucidate its potential role in modulating inflammation occurring in amyotrophic lateral sclerosis (ALS).
Sun May 17 00:00:00 EDT 2020
Activated ROCK/Akt/eNOS and ET-1/ERK pathways in 5-fluorouracil-induced cardiotoxicity: modulation by simvastatin.
Scientific reports
Muhammad RN,Sallam N,El-Abhar HS
PA1-183 was used in Western Blotting to highlight the involvement and crosstalk of several signaling pathways in the 5-FU-induced cardiac injury.
Mon Sep 07 00:00:00 EDT 2020
Activated ROCK/Akt/eNOS and ET-1/ERK pathways in 5-fluorouracil-induced cardiotoxicity: modulation by simvastatin.
Scientific reports
Muhammad RN,Sallam N,El-Abhar HS
PA1-183 was used in Western Blotting to highlight the involvement and crosstalk of several signaling pathways in the 5-FU-induced cardiac injury.
Mon Sep 07 00:00:00 EDT 2020
Enteropathogenic Escherichia coli Infection Induces Diarrhea, Intestinal Damage, Metabolic Alterations, and Increased Intestinal Permeability in a Murine Model.
Frontiers in cellular and infection microbiology
Ledwaba SE,Costa DVS,Bolick DT,Giallourou N,Medeiros PHQS,Swann JR,Traore AN,Potgieter N,Nataro JP,Guerrant RL
PA1-183 was used in Western Blotting to develop a murine infection model treated with antibiotics to mimic clinical outcomes seen in children with EPEC infection.
Thu Jun 17 00:00:00 EDT 2021
Enteropathogenic Escherichia coli Infection Induces Diarrhea, Intestinal Damage, Metabolic Alterations, and Increased Intestinal Permeability in a Murine Model.
Frontiers in cellular and infection microbiology
Ledwaba SE,Costa DVS,Bolick DT,Giallourou N,Medeiros PHQS,Swann JR,Traore AN,Potgieter N,Nataro JP,Guerrant RL
PA1-183 was used in Western Blotting to develop a murine infection model treated with antibiotics to mimic clinical outcomes seen in children with EPEC infection.
Thu Jun 17 00:00:00 EDT 2021
Systematic Development and Optimization of Inhalable Pirfenidone Liposomes for Non-Small Cell Lung Cancer Treatment.
Pharmaceutics
Parvathaneni V,Kulkarni NS,Shukla SK,Farrales PT,Kunda NK,Muth A,Gupta V
PA1-183 was used in Western Blotting to establish the efficacy of cationic liposomes loaded with pirfenidone for non-small cell lung cancer treatment in a bid to provide higher therapeutic and socioeconomic value than current non-small cell lung cancer treatment regimens.
Fri Feb 28 00:00:00 EST 2020
Systematic Development and Optimization of Inhalable Pirfenidone Liposomes for Non-Small Cell Lung Cancer Treatment.
Pharmaceutics
Parvathaneni V,Kulkarni NS,Shukla SK,Farrales PT,Kunda NK,Muth A,Gupta V
PA1-183 was used in Western Blotting to establish the efficacy of cationic liposomes loaded with pirfenidone for non-small cell lung cancer treatment in a bid to provide higher therapeutic and socioeconomic value than current non-small cell lung cancer treatment regimens.
Fri Feb 28 00:00:00 EST 2020
Influences of circulatory factors on intervertebral disc aging phenotype.
Aging
Lei C,Colangelo D,Patil P,Li V,Ngo K,Wang D,Dong Q,Yousefzadeh MJ,Lin H,Lee J,Kang J,Sowa G,Wyss-Coray T,Niedernhofer LJ,Robbins PD,Huffman DM,Vo N
PA1-183 was used in Western Blotting to perform heterochronic parabiosis in mice to study the effects of circulating factors in young and old blood on age-associated intervertebral disc degeneration.
Thu Jun 11 00:00:00 EDT 2020
Influences of circulatory factors on intervertebral disc aging phenotype.
Aging
Lei C,Colangelo D,Patil P,Li V,Ngo K,Wang D,Dong Q,Yousefzadeh MJ,Lin H,Lee J,Kang J,Sowa G,Wyss-Coray T,Niedernhofer LJ,Robbins PD,Huffman DM,Vo N
PA1-183 was used in Western Blotting to perform heterochronic parabiosis in mice to study the effects of circulating factors in young and old blood on age-associated intervertebral disc degeneration.
Thu Jun 11 00:00:00 EDT 2020
A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein.
PLoS genetics
Wilson MH,Rajan S,Danoff A,White RJ,Hensley MR,Quinlivan VH,Recacha R,Thierer JH,Tan FJ,Busch-Nentwich EM,Ruddock L,Hussain MM,Farber SA
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Sat Aug 01 00:00:00 EDT 2020
A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein.
PLoS genetics
Wilson MH,Rajan S,Danoff A,White RJ,Hensley MR,Quinlivan VH,Recacha R,Thierer JH,Tan FJ,Busch-Nentwich EM,Ruddock L,Hussain MM,Farber SA
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Sat Aug 01 00:00:00 EDT 2020
Systemic clearance of p16INK4a -positive senescent cells mitigates age-associated intervertebral disc degeneration.
Aging cell
Patil P,Dong Q,Wang D,Chang J,Wiley C,Demaria M,Lee J,Kang J,Niedernhofer LJ,Robbins PD,Sowa G,Campisi J,Zhou D,Vo N
PA1-183 was used in Western Blotting to determine the relationship between cellular senescence and and age-related intervertebral degeneration.
Sat Jun 01 00:00:00 EDT 2019
Systemic clearance of p16INK4a -positive senescent cells mitigates age-associated intervertebral disc degeneration.
Aging cell
Patil P,Dong Q,Wang D,Chang J,Wiley C,Demaria M,Lee J,Kang J,Niedernhofer LJ,Robbins PD,Sowa G,Campisi J,Zhou D,Vo N
PA1-183 was used in Western Blotting to determine the relationship between cellular senescence and and age-related intervertebral degeneration.
Sat Jun 01 00:00:00 EDT 2019
Role of HDAC1 in the progression of gastric cancer and the correlation with lncRNAs.
Oncology letters
Yu Z,Zeng J,Liu H,Wang T,Yu Z,Chen J
PA1-183 was used in Western Blotting to study the precise role of histone deacetylases in the progression of gastric cancer.
Fri Mar 01 00:00:00 EST 2019
Chronic high-fat diet decreased detrusor mitochondrial respiration and increased nerve-mediated contractions.
Neurourology and urodynamics
Powers SA,Ryan TE,Pak ES,Fraser MO,McClung JM,Hannan JL
PA1-183 was used in Western Blotting to study the impact of a chronic high-fat diet on behavioural voiding patterns, detrusor contractility and mitochondrial function in a male mouse model.
Thu Aug 01 00:00:00 EDT 2019
Pirfenidone suppresses the abnormal activation of human Müller cells after platelet-derived growth factor-BB stimulation.
International journal of ophthalmology
Tao YJ,Chen Q,Wang L,Yang X,Cun Q,Yang WY,Zhong H
PA1-183 was used in Western Blotting to determine the effect of pirfenidone on the activated human Müller cells by platelet-derived growth factor-BB.
Wed Sep 30 00:00:00 EDT 2020
Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis.
eLife
Booth AJR,Yue Z,Eykelenboom JK,Stiff T,Luxton GWG,Hochegger H,Tanaka TU
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Immunocytochemistry
Wed Jul 03 00:00:00 EDT 2019
KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover.
Nature communications
Tapia D,Jiménez T,Zamora C,Espinoza J,Rizzo R,González-Cárdenas A,Fuentes D,Hernández S,Cavieres VA,Soza A,Guzmán F,Arriagada G,Yuseff MI,Mardones GA,Burgos PV,Luini A,González A,Cancino J
PA1-183 was used in Western Blot to elucidate a cellular mechanism by which nutrient and membrane sensing machineries cooperate to sustain Golgi-dependent protein secretion.
Wed Feb 13 00:00:00 EST 2019
Chenodeoxycholic Acid Ameliorates AlCl3-Induced Alzheimer's Disease Neurotoxicity and Cognitive Deterioration via Enhanced Insulin Signaling in Rats.
Molecules (Basel, Switzerland)
Bazzari FH,Abdallah DM,El-Abhar HS
PA1-183 was used in Western Blotting to show CDCA was able to improve insulin sensitivity in the hippocampi of AlCl3-treated rats, which highlights its potential in AD management.
Fri May 24 00:00:00 EDT 2019
Grifolic acid induces mitochondrial membrane potential loss and cell death of RAW264.7 macrophages.
Molecular medicine reports
Zhao Y,Zhang H,Yan A,Zhu J,Liu K,Chen D,Xie R,Xu X,Su X
PA1-183 was used in Western Blotting to conclude grifolic acid may induce macrophage cell death by reducing MMP and by inhibiting ATP production probably in an FFAR4-independent manner.
Thu Feb 01 00:00:00 EST 2018
Downregulation of ROS1 enhances the therapeutic efficacy of arsenic trioxide in acute myeloid leukemia cell lines.
Oncology letters
Li J
PA1-183 was used in Western Blotting to investigate the function of ROS proto-oncogene 1 receptor tyrosine kinase in regulating the migration and proliferation of acute myeloid leukaemia cells through Wnt/Β-catenin signalling, and in arsenic trioxide treatment.
Fri Jun 01 00:00:00 EDT 2018
Blockade of soluble epoxide hydrolase attenuates post-ischemic neuronal hyperexcitation and confers resilience against stroke with TrkB activation.
Scientific reports
Chang LH,Lin HC,Huang SS,Chen IC,Chu KW,Chih CL,Liang YW,Lee YC,Chen YY,Lee YH,Lee IH
Published figure using beta Actin polyclonal antibody (Product # PA1-183) in Western Blot
Mon Jan 08 00:00:00 EST 2018
Red-shifted luciferase-luciferin pairs for enhanced bioluminescence imaging.
Nature methods
Yeh HW,Karmach O,Ji A,Carter D,Martins-Green MM,Ai HW
PA1-183 was used in Western Blotting to describe the development of red-shifted luciferins based on synthetic coelenterazine analogues and corresponding mutants of NanoLuc that enable bright bioluminescence.
Sun Oct 01 00:00:00 EDT 2017
Fenofibrate Administration Reduces Alcohol and Saccharin Intake in Rats: Possible Effects at Peripheral and Central Levels.
Frontiers in behavioral neuroscience
Rivera-Meza M,Muñoz D,Jerez E,Quintanilla ME,Salinas-Luypaert C,Fernandez K,Karahanian E
PA1-183 was used in Western Blotting to identify that reduction of ethanol intake by fenofibrate is a consequence of catalase induction in the liver and central pharmacological effects.
Wed Sep 30 00:00:00 EDT 2020
Unlocking Aspirin's Chemopreventive Activity: Role of Irreversibly Inhibiting Platelet Cyclooxygenase-1.
Cancer prevention research (Philadelphia, Pa.)
Lichtenberger LM,Fang D,Bick RJ,Poindexter BJ,Phan T,Bergeron AL,Pradhan S,Dial EJ,Vijayan KV
PA1-183 was used in Western Blot to study the mechanism by which aspirin mediates its chemopreventative effects for colorectal cancer and possibly other cancers.
Wed Feb 01 00:00:00 EST 2017
Unlocking Aspirin's Chemopreventive Activity: Role of Irreversibly Inhibiting Platelet Cyclooxygenase-1.
Cancer prevention research (Philadelphia, Pa.)
Lichtenberger LM,Fang D,Bick RJ,Poindexter BJ,Phan T,Bergeron AL,Pradhan S,Dial EJ,Vijayan KV
PA1-183 was used in Western Blot to study the mechanism by which aspirin mediates its chemopreventative effects for colorectal cancer and possibly other cancers.
Wed Feb 01 00:00:00 EST 2017
Crocin Inhibits Oxidative Stress and Pro-inflammatory Response of Microglial Cells Associated with Diabetic Retinopathy Through the Activation of PI3K/Akt Signaling Pathway.
Journal of molecular neuroscience : MN
Yang X,Huo F,Liu B,Liu J,Chen T,Li J,Zhu Z,Lv B
PA1183 was used in western blot to assess the role of microglial cells in diabetic retinopathy
Sat Apr 01 00:00:00 EDT 2017
1,25-(OH)2D3 and its analogue BXL-628 inhibit high glucose-induced activation of RhoA/ROCK pathway in HK-2 cells.
Experimental and therapeutic medicine
Zhang W,Yi B,Zhang K,Li A,Yang S,Huang J,Liu J,Zhang H
PA1-183 was used in Immunoprecipitation to demonstrate that 1,25-(OH)2D3 and its analog BXenopus laevis-628 contribute to renoprotection by preventing high glucose-induced EMT and ECM accumulation via inactivating the RhoA/ROCK signaling pathway in vitro.
Mon May 01 00:00:00 EDT 2017
Study of the Effects of Betaine and/or C-Phycocyanin on the Growth of Lung Cancer A549 Cells In Vitro and In Vivo.
Journal of oncology
Bingula R,Dupuis C,Pichon C,Berthon JY,Filaire M,Pigeon L,Filaire E
PA1183 was used in western blot to explore the effects of betaine, C-phycocyanin, and their combined use on the growth of lung cancer cells
Fri Sep 16 00:00:00 EDT 2016
Overexpression of the pituitary tumor transforming gene upregulates metastasis in malignant neoplasms of the human salivary glands.
Experimental and therapeutic medicine
Liu J,Wang Y,He H,Jin W,Zheng R
PA1-183 was used in immunohistochemistry - paraffin section and western blot to examine the contribution of the pituitary tumor transforming gene to salivary gland malignant neoplasms
Sat Aug 01 00:00:00 EDT 2015
