Product References
Paclitaxel Regulates TRPA1 Function and Expression Through PKA and PKC.
Neurochemical research
Sánchez JC,Muñoz LV,Galindo-Márquez ML,Valencia-Vásquez A,García AM
MA1-140 was used in Western Blotting to support the role of the TRPA1 channel in the mechanisms altered by PTX, which can be involved in the process that lead to chemotherapy-induced neuropathy.
Sun Jan 01 00:00:00 EST 2023
Pancreatic RECK inactivation promotes cancer formation, epithelial-mesenchymal transition, and metastasis.
The Journal of clinical investigation
Masuda T,Fukuda A,Yamakawa G,Omatsu M,Namikawa M,Sono M,Fukunaga Y,Nagao M,Araki O,Yoshikawa T,Ogawa S,Masuo K,Goto N,Hiramatsu Y,Muta Y,Tsuda M,Maruno T,Nakanishi Y,Masui T,Hatano E,Matsuzaki T,Noda M,Seno H
MA1-140 was used in Western Blot to establish the authenticity of RECK as a pancreatic tumor suppressor, provide insights into its underlying mechanisms, and support the idea that RECK could be an important therapeutic effector against human PDAC.
Fri Sep 15 00:00:00 EDT 2023
Pancreatic RECK inactivation promotes cancer formation, epithelial-mesenchymal transition, and metastasis.
The Journal of clinical investigation
Masuda T,Fukuda A,Yamakawa G,Omatsu M,Namikawa M,Sono M,Fukunaga Y,Nagao M,Araki O,Yoshikawa T,Ogawa S,Masuo K,Goto N,Hiramatsu Y,Muta Y,Tsuda M,Maruno T,Nakanishi Y,Masui T,Hatano E,Matsuzaki T,Noda M,Seno H
MA1-140 was used in Western Blot to establish the authenticity of RECK as a pancreatic tumor suppressor, provide insights into its underlying mechanisms, and support the idea that RECK could be an important therapeutic effector against human PDAC.
Fri Sep 15 00:00:00 EDT 2023
Cholecystokinin Receptor Antagonist Induces Pancreatic Stellate Cell Plasticity Rendering the Tumor Microenvironment Less Oncogenic.
Cancers
Jolly G,Duka T,Shivapurkar N,Chen W,Bansal S,Cheema A,Smith JP
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Thu May 18 00:00:00 EDT 2023
Multi-omics analysis identifies RFX7 targets involved in tumor suppression and neuronal processes.
Cell death discovery
Schwab K,Coronel L,Riege K,Sacramento EK,Rahnis N,Häckes D,Cirri E,Groth M,Hoffmann S,Fischer M
MA1-140 was used in Western Blotting to reveal RFX7 as a mechanistic link that enables the activation of these genes in response to p53 signaling.
Fri Mar 03 00:00:00 EST 2023
Absence of Scaffold Protein Tks4 Disrupts Several Signaling Pathways in Colon Cancer Cells.
International journal of molecular sciences
Jacksi M,Schad E,Buday L,Tantos A
MA1-140 was used in Western Blotting to show a significant perturbation of gene expression upon the deletion of Tks4, suggesting the involvement of different signal transduction pathways over the well-known EGFR signaling.
Mon Jan 09 00:00:00 EST 2023
Creatine kinase brain-type regulates BCAR1 phosphorylation to facilitate DNA damage repair.
iScience
Yang B,Zhang W,Sun L,Lu B,Yin C,Zhang Y,Jiang H
MA1-140 was used in Western Blot to reveal the possible role of CKB independently of its metabolic function and depict the potential pathway of CKB-BCAR1-RBBP4 operating in DNA damage repair.
Fri May 19 00:00:00 EDT 2023
Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction.
Science advances
Fan M,Yang K,Wang X,Chen L,Gill PS,Ha T,Liu L,Lewis NH,Williams DL,Li C
MA1-140 was used in Western Blot to conclude that lactate acts as an important molecule that up-regulates cardiac.
Fri Feb 03 00:00:00 EST 2023
Breviscapine alleviates podocyte injury by inhibiting NF-κB/NLRP3-mediated pyroptosis in diabetic nephropathy.
PeerJ
Sun L,Ding M,Chen F,Zhu D,Xie X
MA1-140 was used in Western Blotting to demonstrate that Bre alleviates HG-induced podocyte injury and improves renal function in diabetic mice, at least in part by inhibiting NF-κB/NLRP3-mediated pyroptosis.
Mon Feb 27 00:00:00 EST 2023
Gene therapy targeting miR‑212‑3p exerts therapeutic effects on MAFLD similar to those of exercise.
International journal of molecular medicine
Sun B,Zhang Y,Zhang M,Liu R,Yang W
MA1-140 was used in Western Blotting to demonstrate that miR-212-3p plays a key role in the effects of exercise on MAFLD.
Wed Feb 01 00:00:00 EST 2023
Gene therapy targeting miR‑212‑3p exerts therapeutic effects on MAFLD similar to those of exercise.
International journal of molecular medicine
Sun B,Zhang Y,Zhang M,Liu R,Yang W
MA1-140 was used in Western Blotting to demonstrate that miR-212-3p plays a key role in the effects of exercise on MAFLD.
Wed Feb 01 00:00:00 EST 2023
Convergent alteration of the mesenchymal stem cell heterogeneity in adipose tissue during aging.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liu Q,Zhao Y,Wang Q,Yan L,Fu X,Xiao R
MA1-140 was used in Western Blotting to delineate the complex biological processes of ASCs aging and shed light on better regenerative and therapeutic applications of ASCs.
Tue Aug 01 00:00:00 EDT 2023
CCDC86 is a novel Ki-67-interacting protein important for cell division.
Journal of cell science
Stamatiou K,Chmielewska A,Ohta S,Earnshaw WC,Vagnarelli P
MA1-140 was used in Western Blotting to identify a novel chromosome periphery-associated protein, CCDC86 (also known as cyclon).
Sun Jan 15 00:00:00 EST 2023
Cyclin O promotes lung cancer progression and cetuximab resistance via cell cycle regulation and CDK13 interaction.
Journal of thoracic disease
Jiang J,Yu W,Fang T,Li Y,Liang J,Zhao R,Feng Z,Wang J,Tian H
MA1-140 was used in Immunohistochemistry to suggest that CCNO may be a driver in the development of LUAD and that its function is related to CDK13 interaction that promotes proliferation signaling activation.
Fri Apr 28 00:00:00 EDT 2023
Cyclin O promotes lung cancer progression and cetuximab resistance via cell cycle regulation and CDK13 interaction.
Journal of thoracic disease
Jiang J,Yu W,Fang T,Li Y,Liang J,Zhao R,Feng Z,Wang J,Tian H
MA1-140 was used in Immunohistochemistry to suggest that CCNO may be a driver in the development of LUAD and that its function is related to CDK13 interaction that promotes proliferation signaling activation.
Fri Apr 28 00:00:00 EDT 2023
Cyclin O promotes lung cancer progression and cetuximab resistance via cell cycle regulation and CDK13 interaction.
Journal of thoracic disease
Jiang J,Yu W,Fang T,Li Y,Liang J,Zhao R,Feng Z,Wang J,Tian H
MA1-140 was used in Immunohistochemistry to suggest that CCNO may be a driver in the development of LUAD and that its function is related to CDK13 interaction that promotes proliferation signaling activation.
Fri Apr 28 00:00:00 EDT 2023
SARS-CoV-2 Permissive glioblastoma cell line for high throughput antiviral screening.
Antiviral research
Vanhulle E,Stroobants J,Provinciael B,Camps A,Noppen S,Maes P,Vermeire K
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Fri Jul 01 00:00:00 EDT 2022
Hypoxia-inducible factor-1 alpha expression is induced by IL-2 via the PI3K/mTOR pathway in hypoxic NK cells and supports effector functions in NKL cells and ex vivo expanded NK cells.
Cancer immunology, immunotherapy : CII
Cluff E,Magdaleno CC,Fernandez E,House T,Swaminathan S,Varadaraj A,Rajasekaran N
MA1-140 was used in Western Blot to highlight that HIF-1α stabilization in hypoxia maximizes NK cell effector function and raises the prospect of NK cells as ideal therapeutic candidates for solid tumors.
Mon Aug 01 00:00:00 EDT 2022
Reduced DNAJC3 Expression Affects Protein Translocation across the ER Membrane and Attenuates the Down-Modulating Effect of the Translocation Inhibitor Cyclotriazadisulfonamide.
International journal of molecular sciences
Pauwels E,Provinciael B,Camps A,Hartmann E,Vermeire K
MA1-140 was used in Western Blot to study the impact of altered DNAJC3 protein levels on the inhibitory activity of cyclotriazadisulfonamide.
Thu Jan 06 00:00:00 EST 2022
Reduced DNAJC3 Expression Affects Protein Translocation across the ER Membrane and Attenuates the Down-Modulating Effect of the Translocation Inhibitor Cyclotriazadisulfonamide.
International journal of molecular sciences
Pauwels E,Provinciael B,Camps A,Hartmann E,Vermeire K
MA1-140 was used in Western Blot to study the impact of altered DNAJC3 protein levels on the inhibitory activity of cyclotriazadisulfonamide.
Thu Jan 06 00:00:00 EST 2022
Proglumide Reverses Nonalcoholic Steatohepatitis by Interaction with the Farnesoid X Receptor and Altering the Microbiome.
International journal of molecular sciences
Gay MD,Cao H,Shivapurkar N,Dakshanamurthy S,Kallakury B,Tucker RD,Kwagyan J,Smith JP
MA1-140 was used in Western Blot to study the role of proglumide, a cholecystokinin receptor inhibitor, in a murine model of nonalcoholic steatohepatitis and its interaction at farnesoid X receptor.
Tue Feb 08 00:00:00 EST 2022
Proglumide Reverses Nonalcoholic Steatohepatitis by Interaction with the Farnesoid X Receptor and Altering the Microbiome.
International journal of molecular sciences
Gay MD,Cao H,Shivapurkar N,Dakshanamurthy S,Kallakury B,Tucker RD,Kwagyan J,Smith JP
MA1-140 was used in Western Blot to study the role of proglumide, a cholecystokinin receptor inhibitor, in a murine model of nonalcoholic steatohepatitis and its interaction at farnesoid X receptor.
Tue Feb 08 00:00:00 EST 2022
The phosphatase and tensin homolog gene inserted between NP and P gene of recombinant New castle disease virus oncolytic effect test to glioblastoma cell and xenograft mouse model.
Virology journal
Jang SH,Jung BK,An YH,Jang H
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Sat Jan 29 00:00:00 EST 2022
The phosphatase and tensin homolog gene inserted between NP and P gene of recombinant New castle disease virus oncolytic effect test to glioblastoma cell and xenograft mouse model.
Virology journal
Jang SH,Jung BK,An YH,Jang H
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Sat Jan 29 00:00:00 EST 2022
Constricted migration is associated with stable 3D genome structure differences in cancer cells.
EMBO reports
Golloshi R,Playter C,Freeman TF,Das P,Raines TI,Garretson JH,Thurston D,McCord RP
MA1-140 was used in Western Blotting to suggest that consistent types of chromosome structure changes are induced or selected by passage through constrictions and that these may epigenetically encode stable differences in gene expression and cellular migration phenotype.
Thu Oct 06 00:00:00 EDT 2022
Immortalized human choroid plexus endothelial cells enable an advanced endothelial-epithelial two-cell type in vitro model of the choroid plexus.
iScience
Muranyi W,Schwerk C,Herold R,Stump-Guthier C,Lampe M,Fallier-Becker P,Weiß C,Sticht C,Ishikawa H,Schroten H
MA1-140 was used in Immunocytochemistry-immunoflourescence to suggest that iHCPEnC present a tool that will contribute to the understanding of CP organ functions, especially endothelial-epithelial interplay.
Fri Jun 17 00:00:00 EDT 2022
SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition.
Biosensors & bioelectronics
Azad T,Singaravelu R,Fekete EEF,Taha Z,Rezaei R,Arulanandam R,Boulton S,Diallo JS,Ilkow CS,Bell JC
MA1-140 was used in Western Blotting to develop a novel bioluminescence-based biosensor to probe a key host-virus interaction during viral entry.
Sat May 15 00:00:00 EDT 2021
SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition.
Biosensors & bioelectronics
Azad T,Singaravelu R,Fekete EEF,Taha Z,Rezaei R,Arulanandam R,Boulton S,Diallo JS,Ilkow CS,Bell JC
MA1-140 was used in Western Blotting to develop a novel bioluminescence-based biosensor to probe a key host-virus interaction during viral entry.
Sat May 15 00:00:00 EDT 2021
α-synuclein aggregates induce c-Abl activation and dopaminergic neuronal loss by a feed-forward redox stress mechanism.
Progress in neurobiology
Ghosh S,Won SJ,Wang J,Fong R,Butler NJM,Moss A,Wong C,Pan J,Sanchez J,Huynh A,Wu L,Manfredsson FP,Swanson RA
MA1-140 was used in Western Blot to determine whether c-Abl activation mediates interactions between redox stress and α-synuclein aggregate formation.
Thu Jul 01 00:00:00 EDT 2021
Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer.
Gynecologic oncology
Gupta VG,Hirst J,Petersen S,Roby KF,Kusch M,Zhou H,Clive ML,Jewell A,Pathak HB,Godwin AK,Wilson AJ,Crispens MA,Cybulla E,Vindigni A,Fuh KC,Khabele D
MA1-140 was used in Western Blotting to conclude that Entinostat inhibits HR repair by reducing BRCA1 expression and stalling replication fork progression, leading to irreparable DNA damage and ultimate cell death.
Thu Jul 01 00:00:00 EDT 2021
Fibronectin assembly regulates lumen formation in breast acini.
Journal of cellular biochemistry
Magdaleno C,House T,Pawar JS,Carvalho S,Rajasekaran N,Varadaraj A
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Sat May 01 00:00:00 EDT 2021
Protective effects of gastrodin pretreatment on mouse hepatic ischemia-reperfusion occurring through antioxidant and anti-apoptotic mechanisms.
Experimental and therapeutic medicine
Sun B,Jiang J,Zhu X,Yang D,Cui Z,Zhang Y,Zhang M,Qian Y,Liu R,Yang W
MA1-140 was used in Western Blotting to show protective effects from Gas pretreatment is observed in hepatic ischemia-reperfusion injury mouse models.
Sat May 01 00:00:00 EDT 2021
miR-377 inhibition enhances the survival of trophoblast cells via upregulation of FNDC5 in gestational diabetes mellitus.
Open medicine (Warsaw, Poland)
Hua Z,Li D,Wu A,Cao T,Luo S
MA1-140 was used in Western Blot to investigate the effects of microRNA-377 (miR-377-3p) and fibronectin type III domain containing 5 (FNDC5) in regulating the cell growth of trophoblasts under high glucose conditions during the development of gestational diabetes mellitus.
Tue Apr 06 00:00:00 EDT 2021
miR-377 inhibition enhances the survival of trophoblast cells via upregulation of FNDC5 in gestational diabetes mellitus.
Open medicine (Warsaw, Poland)
Hua Z,Li D,Wu A,Cao T,Luo S
MA1-140 was used in Western Blot to investigate the effects of microRNA-377 (miR-377-3p) and fibronectin type III domain containing 5 (FNDC5) in regulating the cell growth of trophoblasts under high glucose conditions during the development of gestational diabetes mellitus.
Tue Apr 06 00:00:00 EDT 2021
The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation.
Nature communications
Xu X,Ni K,He Y,Ren J,Sun C,Liu Y,Aladjem MI,Burkett S,Finney R,Ding X,Sharan SK,Muegge K
MA1-140 was used in Western Blot to demonstrate the pathogenic effects of LSH depletion: a causative mutation of Immunodeficiency Centromeric Instability Facial Anomalies 4 syndrome.
Thu Jun 10 00:00:00 EDT 2021
The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation.
Nature communications
Xu X,Ni K,He Y,Ren J,Sun C,Liu Y,Aladjem MI,Burkett S,Finney R,Ding X,Sharan SK,Muegge K
MA1-140 was used in Western Blot to demonstrate the pathogenic effects of LSH depletion: a causative mutation of Immunodeficiency Centromeric Instability Facial Anomalies 4 syndrome.
Thu Jun 10 00:00:00 EDT 2021
Cholecystokinin Receptor Antagonist Improves Efficacy of Chemotherapy in Murine Models of Pancreatic Cancer by Altering the Tumor Microenvironment.
Cancers
Malchiodi ZX,Cao H,Gay MD,Safronenka A,Bansal S,Tucker RD,Weinberg BA,Cheema A,Shivapurkar N,Smith JP
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Thu Sep 30 00:00:00 EDT 2021
Mesenchymal Stem Cell exosome delivered Zinc Finger Protein activation of cystic fibrosis transmembrane conductance regulator.
Journal of extracellular vesicles
Villamizar O,Waters SA,Scott T,Grepo N,Jaffe A,Morris KV
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Fri Jan 01 00:00:00 EST 2021
Mesenchymal Stem Cell exosome delivered Zinc Finger Protein activation of cystic fibrosis transmembrane conductance regulator.
Journal of extracellular vesicles
Villamizar O,Waters SA,Scott T,Grepo N,Jaffe A,Morris KV
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Fri Jan 01 00:00:00 EST 2021
ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H+-ATPases is essential for brain development in humans and mice.
Nature communications
Aoto K,Kato M,Akita T,Nakashima M,Mutoh H,Akasaka N,Tohyama J,Nomura Y,Hoshino K,Ago Y,Tanaka R,Epstein O,Ben-Haim R,Heyman E,Miyazaki T,Belal H,Takabayashi S,Ohba C,Takata A,Mizuguchi T,Miyatake S,Miyake N,Fukuda A,Matsumoto N,Saitsu H
MA1-140 was used in Western Blot to identify de novo and biallelic variants in ATP6V0A1, encoding the a1-subunit of the V0 domain, in individuals with developmental and epileptic encephalopathy who showed various degrees of intellectual disability, developmental delay, and epilepsy.
Thu Apr 08 00:00:00 EDT 2021
ATP6V0A1 encoding the a1-subunit of the V0 domain of vacuolar H+-ATPases is essential for brain development in humans and mice.
Nature communications
Aoto K,Kato M,Akita T,Nakashima M,Mutoh H,Akasaka N,Tohyama J,Nomura Y,Hoshino K,Ago Y,Tanaka R,Epstein O,Ben-Haim R,Heyman E,Miyazaki T,Belal H,Takabayashi S,Ohba C,Takata A,Mizuguchi T,Miyatake S,Miyake N,Fukuda A,Matsumoto N,Saitsu H
MA1-140 was used in Western Blot to identify de novo and biallelic variants in ATP6V0A1, encoding the a1-subunit of the V0 domain, in individuals with developmental and epileptic encephalopathy who showed various degrees of intellectual disability, developmental delay, and epilepsy.
Thu Apr 08 00:00:00 EDT 2021
Green Synthesized Honokiol Transfersomes Relieve the Immunosuppressive and Stem-Like Cell Characteristics of the Aggressive B16F10 Melanoma.
International journal of nanomedicine
Ezzeldeen Y,Swidan S,ElMeshad A,Sebak A
MA1-140 was used in Western Blot to fabricate Honokiol transfersomes for topical treatment of melanoma.
Wed Nov 24 00:00:00 EST 2021
Green Synthesized Honokiol Transfersomes Relieve the Immunosuppressive and Stem-Like Cell Characteristics of the Aggressive B16F10 Melanoma.
International journal of nanomedicine
Ezzeldeen Y,Swidan S,ElMeshad A,Sebak A
MA1-140 was used in Western Blot to fabricate Honokiol transfersomes for topical treatment of melanoma.
Wed Nov 24 00:00:00 EST 2021
A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide.
Molecular & cellular proteomics : MCP
Pauwels E,Rutz C,Provinciael B,Stroobants J,Schols D,Hartmann E,Krause E,Stephanowitz H,Schülein R,Vermeire K
MA1-140 was used in Immunocytochemistry, Immunoprecipitation, Western Blot to analyze how many proteins are sensitive to CADA.
Thu Mar 24 00:00:00 EDT 2022
A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide.
Molecular & cellular proteomics : MCP
Pauwels E,Rutz C,Provinciael B,Stroobants J,Schols D,Hartmann E,Krause E,Stephanowitz H,Schülein R,Vermeire K
MA1-140 was used in Immunocytochemistry, Immunoprecipitation, Western Blot to analyze how many proteins are sensitive to CADA.
Thu Mar 24 00:00:00 EDT 2022
Liposomes Loaded with Everolimus and Coated with Hyaluronic Acid: A Promising Approach for Lung Fibrosis.
International journal of molecular sciences
Pandolfi L,Marengo A,Japiassu KB,Frangipane V,Tsapis N,Bincoletto V,Codullo V,Bozzini S,Morosini M,Lettieri S,Vertui V,Piloni D,Arpicco S,Fattal E,Meloni F
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Tue Jul 20 00:00:00 EDT 2021
Chronic Inhibition of FAAH Reduces Depressive-Like Behavior and Improves Dentate Gyrus Proliferation after Chronic Unpredictable Stress Exposure.
Behavioural neurology
Tejeda-Martínez AR,Viveros-Paredes JM,Hidalgo-Franco GV,Pardo-González E,Chaparro-Huerta V,González-Castañeda RE,Flores-Soto ME
MA1-140 was used in Western Blotting to show that the chronic inhibition of fatty acid amide hydrolase (FAAH) generate an antidepressant effect, promoting neural progenitor proliferation and brain-derived neurotrophic factor (BDNF) expression, while reducing adrenal gland weight and oxidative stress in mice under the chronic unpredictable stress model.
Wed Aug 18 00:00:00 EDT 2021
Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis.
Nature biomedical engineering
Koldobskiy MA,Jenkinson G,Abante J,Rodriguez DiBlasi VA,Zhou W,Pujadas E,Idrizi A,Tryggvadottir R,Callahan C,Bonifant CL,Rabin KR,Brown PA,Ji H,Goutsias J,Feinberg AP
MA1-140 was used in Western Blot to suggest that an epigenetically driven gene-regulation network, with UHRF1 (ubiquitin-like with PHD and RING finger domains 1) as a central node, links genetic drivers and epigenetic mediators in ALL.
Thu Apr 01 00:00:00 EDT 2021
Vaccination with Polyclonal Antibody Stimulator (PAS) Prevents Pancreatic Carcinogenesis in the KRAS Mouse Model.
Cancer prevention research (Philadelphia, Pa.)
Smith JP,Cao H,Chen W,Kallakury B,Phillips T,Sutton L,Cato A
MA1-140 was used in Western Blot to show that the gastrointestinal peptide gastrin, which is only expressed in the fetal pancreas and not in the adult pancreas, is activated during pancreatic carcinogenesis where it stimulates growth in an autocrine fashion.
Fri Oct 01 00:00:00 EDT 2021
Discovery of Sulforaphane as an Inducer of Ferroptosis in U-937 Leukemia Cells: Expanding Its Anticancer Potential.
Cancers
Greco G,Schnekenburger M,Catanzaro E,Turrini E,Ferrini F,Sestili P,Diederich M,Fimognari C
MA1-140 was used in Western Blotting to explore the capacity of sulforaphane to induce non-apoptotic cell death modalities.
Fri Dec 24 00:00:00 EST 2021
Micro-RNA-451 Reduces Proliferation of B-CPAP Human Papillary Thyroid Cancer Cells by Downregulating Expression of Activating Transcription Factor 2.
Medical science monitor : international medical journal of experimental and clinical research
Zhang MF,Fei ZW,Huang L
MA1-140 was used in Western Blot to investigate the molecular mechanism associated with the effects of miR-451 on B-CPAP human PTC cells in vitro.
Tue Mar 16 00:00:00 EDT 2021
Anti-Aggregative Effect of the Antioxidant DJ-1 on the TPPP/p25-Derived Pathological Associations of Alpha-Synuclein.
Cells
Oláh J,Lehotzky A,Szénási T,Ovádi J
MA1-140 was used in Western Blot to reveal the protective effect of DJ-1 against toxic SYN assemblies, which assigns a new function to the antioxidant sensor DJ-1.
Wed Oct 27 00:00:00 EDT 2021
Genetic screening of children with marrow failure. The role of primary Immunodeficiencies.
American journal of hematology
Miano M,Grossi A,Dell'Orso G,Lanciotti M,Fioredda F,Palmisani E,Lanza T,Guardo D,Beccaria A,Ravera S,Cossu V,Terranova P,Giona F,Santopietro M,Cappelli E,Ceccherini I,Dufour C
MA1-140 was used in Western Blotting to show that patients with single/multi-lineage MF may have underlying PIDs in a considerable number of cases and that MF may represent a relevant clinical sign in patients with PIDs, thus widening their clinical phenotype.
Wed Sep 01 00:00:00 EDT 2021
Expression of STOML2 promotes proliferation and glycolysis of multiple myeloma cells via upregulating PAI-1.
Journal of orthopaedic surgery and research
Zhang H,Wu G,Feng J,Lu X,Liu P
MA1-140 was used in Western Blotting to demonstrate that STOML2 silencing inhibits cell proliferation and glycolysis through downregulation of PAI-1 expression, suggesting a new therapeutic target for MM.
Sat Nov 13 00:00:00 EST 2021
PP2A Regulates Phosphorylation-Dependent Isomerization of Cytoplasmic and Mitochondrial-Associated ATR by Pin1 in DNA Damage Responses.
Frontiers in cell and developmental biology
Makinwa Y,Cartwright BM,Musich PR,Li Z,Biswas H,Zou Y
MA1-140 was used in Western Blotting to report that Pin1's activity on cis ATR requires the phosphorylation of the S428 residue of ATR and describe the molecular mechanism by which Pin1-mediated ATR isomerization in the cytoplasm is regulated.
Fri Oct 02 00:00:00 EDT 2020
PP2A Regulates Phosphorylation-Dependent Isomerization of Cytoplasmic and Mitochondrial-Associated ATR by Pin1 in DNA Damage Responses.
Frontiers in cell and developmental biology
Makinwa Y,Cartwright BM,Musich PR,Li Z,Biswas H,Zou Y
MA1-140 was used in Western Blotting to report that Pin1's activity on cis ATR requires the phosphorylation of the S428 residue of ATR and describe the molecular mechanism by which Pin1-mediated ATR isomerization in the cytoplasm is regulated.
Fri Oct 02 00:00:00 EDT 2020
Nicotine directly affects milk production in lactating mammary epithelial cells concurrently with inactivation of STAT5 and glucocorticoid receptor in vitro.
Toxicology in vitro : an international journal published in association with BIBRA
Kobayashi K,Tsugami Y,Suzuki N,Suzuki T,Nishimura T
MA1-140 was used in Western Blot to investigate whether nicotine directly affects milk production in lactating mammary epithelial cells.
Sun Mar 01 00:00:00 EST 2020
A Cholecystokinin Receptor Antagonist Halts Nonalcoholic Steatohepatitis and Prevents Hepatocellular Carcinoma.
Digestive diseases and sciences
Tucker RD,Ciofoaia V,Nadella S,Gay MD,Cao H,Huber M,Safronenka A,Shivapurkar N,Kallakury B,Kruger AJ,Kroemer AHK,Smith JP
MA1-140 was used in Western Blotting to support the novel role of CCK receptors in the pathogenesis of NASH and HCC.
Wed Jan 01 00:00:00 EST 2020
Comparison of a human neuronal model proteome upon Japanese encephalitis or West Nile Virus infection and potential role of mosquito saliva in neuropathogenesis.
PloS one
Besson B,Basset J,Gatellier S,Chabrolles H,Chaze T,Hourdel V,Matondo M,Pardigon N,Choumet V
MA1-140 was used in Western Blotting to identify proteins differentially expressed upon JEV (gp-3, RP9) or WNV (IS98) infection of human neuroblastoma cells.
Thu Jul 30 00:00:00 EDT 2020
Comparison of a human neuronal model proteome upon Japanese encephalitis or West Nile Virus infection and potential role of mosquito saliva in neuropathogenesis.
PloS one
Besson B,Basset J,Gatellier S,Chabrolles H,Chaze T,Hourdel V,Matondo M,Pardigon N,Choumet V
MA1-140 was used in Western Blotting to identify proteins differentially expressed upon JEV (gp-3, RP9) or WNV (IS98) infection of human neuroblastoma cells.
Thu Jul 30 00:00:00 EDT 2020
Modification of Adenosine196 by Mettl3 Methyltransferase in the 5'-External Transcribed Spacer of 47S Pre-rRNA Affects rRNA Maturation.
Cells
Sergeeva O,Sergeev P,Melnikov P,Prikazchikova T,Dontsova O,Zatsepin T
MA1-140 was used in Western Blotting to explore the Mettl3 methyl transferase-dependent mechanisms involved in rRNA maturation.
Fri Apr 24 00:00:00 EDT 2020
Modification of Adenosine196 by Mettl3 Methyltransferase in the 5'-External Transcribed Spacer of 47S Pre-rRNA Affects rRNA Maturation.
Cells
Sergeeva O,Sergeev P,Melnikov P,Prikazchikova T,Dontsova O,Zatsepin T
MA1-140 was used in Western Blotting to explore the Mettl3 methyl transferase-dependent mechanisms involved in rRNA maturation.
Fri Apr 24 00:00:00 EDT 2020
Intrinsic ATR signaling shapes DNA end resection and suppresses toxic DNA-PKcs signaling.
NAR cancer
Dibitetto D,Sims JR,Ascenção CFR,Feng K,Kim D,Oberly S,Freire R,Smolka MB
MA1-140 was used in Immunocytochemistry-immunoflourescence to reveal a key pro-resection function for ATR and define how ATR inhibitors can be used for effective manipulation of DNA end resection capacity and DNA repair outcomes in cancer cells.
Mon Jun 01 00:00:00 EDT 2020
Intrinsic ATR signaling shapes DNA end resection and suppresses toxic DNA-PKcs signaling.
NAR cancer
Dibitetto D,Sims JR,Ascenção CFR,Feng K,Kim D,Oberly S,Freire R,Smolka MB
MA1-140 was used in Immunocytochemistry-immunoflourescence to reveal a key pro-resection function for ATR and define how ATR inhibitors can be used for effective manipulation of DNA end resection capacity and DNA repair outcomes in cancer cells.
Mon Jun 01 00:00:00 EDT 2020
The Role of Orai1 in Regulating Sarcoplasmic Calcium Release, Mitochondrial Morphology and Function in Myostatin Deficient Skeletal Muscle.
Frontiers in physiology
Sztretye M,Singlár Z,Balogh N,Kis G,Szentesi P,Angyal Á,Balatoni I,Csernoch L,Dienes B
MA1-140 was used in Western Blotting to show that reduced function and/or expression of SOCE partners (in this study Orai1) and mitochondrial defects could play an important role in muscle weakness and degeneration associated with certain pathologies, perhaps including loss of function of the neuromuscular junction and aging..
Mon Jan 11 00:00:00 EST 2021
The Role of Orai1 in Regulating Sarcoplasmic Calcium Release, Mitochondrial Morphology and Function in Myostatin Deficient Skeletal Muscle.
Frontiers in physiology
Sztretye M,Singlár Z,Balogh N,Kis G,Szentesi P,Angyal Á,Balatoni I,Csernoch L,Dienes B
MA1-140 was used in Western Blotting to show that reduced function and/or expression of SOCE partners (in this study Orai1) and mitochondrial defects could play an important role in muscle weakness and degeneration associated with certain pathologies, perhaps including loss of function of the neuromuscular junction and aging..
Mon Jan 11 00:00:00 EST 2021
Curcumin derivative C212 inhibits Hsp90 and eliminates both growing and quiescent leukemia cells in deep dormancy.
Cell communication and signaling : CCS
Liu B,Shen Y,Huang H,Croce KD,Wu M,Fan Y,Liu Y,Xu J,Yao G
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Tue Sep 29 00:00:00 EDT 2020
Systemic Delivery of AAV-Fdxr Mitigates the Phenotypes of Mitochondrial Disorders in Fdxr Mutant Mice.
Molecular therapy. Methods & clinical development
Yang L,Slone J,Zou W,Queme LF,Jankowski MP,Yin F,Huang T
MA1-140 was used in Western Blotting to provides substantial support for the translation of AAV-based Fdxr gene therapy into clinical applications.
Fri Sep 11 00:00:00 EDT 2020
Systemic Delivery of AAV-Fdxr Mitigates the Phenotypes of Mitochondrial Disorders in Fdxr Mutant Mice.
Molecular therapy. Methods & clinical development
Yang L,Slone J,Zou W,Queme LF,Jankowski MP,Yin F,Huang T
MA1-140 was used in Western Blotting to provides substantial support for the translation of AAV-based Fdxr gene therapy into clinical applications.
Fri Sep 11 00:00:00 EDT 2020
Loading Imatinib inside targeted nanoparticles to prevent Bronchiolitis Obliterans Syndrome.
Scientific reports
Pandolfi L,Fusco R,Frangipane V,D'Amico R,Giustra M,Bozzini S,Morosini M,D'Amato M,Cova E,Ferrario G,Morbini P,Colombo M,Prosperi D,Viglio S,Piloni D,Di Paola R,Cuzzocrea S,Meloni F
MA1-140 was used in Western Blotting to show imatinib-loaded gold nanoparticles reduced lymphocytic and neutrophil infiltration and mast cells degranulation.
Thu Nov 26 00:00:00 EST 2020
Loading Imatinib inside targeted nanoparticles to prevent Bronchiolitis Obliterans Syndrome.
Scientific reports
Pandolfi L,Fusco R,Frangipane V,D'Amico R,Giustra M,Bozzini S,Morosini M,D'Amato M,Cova E,Ferrario G,Morbini P,Colombo M,Prosperi D,Viglio S,Piloni D,Di Paola R,Cuzzocrea S,Meloni F
MA1-140 was used in Western Blotting to show imatinib-loaded gold nanoparticles reduced lymphocytic and neutrophil infiltration and mast cells degranulation.
Thu Nov 26 00:00:00 EST 2020
Radiation-induced DNA damage and repair effects on 3D genome organization.
Nature communications
Sanders JT,Freeman TF,Xu Y,Golloshi R,Stallard MA,Hill AM,San Martin R,Balajee AS,McCord RP
MA1-140 was used in Western Blotting to investigate the impact of DNA damage response and repair on genome folding in wild type and ATM patient cells.
Wed Dec 02 00:00:00 EST 2020
Murine Long Noncoding RNA Morrbid Contributes in the Regulation of NRAS Splicing in Hepatocytes In Vitro.
International journal of molecular sciences
Fefilova A,Melnikov P,Prikazchikova T,Abakumova T,Kurochkin I,Mazin PV,Ziganshin R,Sergeeva O,Zatsepin TS
MA1-140 was used in Western Blotting to propose the regulation mechanism of NRAS splicing in murine hepatocytes by alternative splicing coupled with the NMD pathway with the input of Morrbid lncRNA.
Wed Aug 05 00:00:00 EDT 2020
Adverse Effects of Coumestrol and Genistein on Mammary Morphogenesis and Future Milk Production Ability of Mammary Epithelial Cells.
Advanced biosystems
Kumai A,Tsugami Y,Wakasa H,Suzuki N,Suzuki T,Nishimura T,Kobayashi K
MA1-140 was used in Immunohistochemistry to investigate the role of phytoestrogens on mammary structure development and milk production in mammary epithelial cells.
Wed Apr 01 00:00:00 EDT 2020
HIFα independent mechanisms in renal carcinoma cells modulate divergent outcomes in fibronectin assembly mediated by hypoxia and CoCl2.
Scientific reports
Magdaleno C,Dixon L,Rajasekaran N,Varadaraj A
MA1-140 was used in Immunocytochemistry-immunoflourescence to systematically reexamine the role of hypoxia mimetics as experimental substitutes for hypoxia and provides new findings on HIFα stabilization and the FN matrix in the context of renal cancer.
Thu Oct 29 00:00:00 EDT 2020
HIFα independent mechanisms in renal carcinoma cells modulate divergent outcomes in fibronectin assembly mediated by hypoxia and CoCl2.
Scientific reports
Magdaleno C,Dixon L,Rajasekaran N,Varadaraj A
MA1-140 was used in Immunocytochemistry-immunoflourescence to systematically reexamine the role of hypoxia mimetics as experimental substitutes for hypoxia and provides new findings on HIFα stabilization and the FN matrix in the context of renal cancer.
Thu Oct 29 00:00:00 EDT 2020
Prodrug-Loaded Zirconium Carbide Nanosheets as a Novel Biophotonic Nanoplatform for Effective Treatment of Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Liu Q,Xie Z,Qiu M,Shim I,Yang Y,Xie S,Yang Q,Wang D,Chen S,Fan T,Ding B,Guo Z,Adah D,Yao X,Zhang Y,Wu H,Wu Z,Wei C,Wang H,Kim HS,Zou Q,Yan Q,Cai Z,Kim JS,Liu LP,Zhang H,Cao Y
MA1-140 was used in Western Blotting to unravel a promising biophotonic strategy for precision treatment of cancer.
Tue Dec 01 00:00:00 EST 2020
Vaccine against gastrin, a polyclonal antibody stimulator, decreases pancreatic cancer metastases.
American journal of physiology. Gastrointestinal and liver physiology
Osborne N,Sundseth R,Gay MD,Cao H,Tucker RD,Nadella S,Wang S,Liu X,Kroemer A,Sutton L,Cato A,Smith JP
MA1-140 was used in Western Blotting to investigate the effects of lone and combined treatment of polyclonal antibody stimulator, an anti-gastrin cancer vaccine, on pancreatic cancer growth, metastases, and the tumor microenvironment.
Fri Nov 01 00:00:00 EDT 2019
Characterization of polyclonal antibodies to Herpes Simplex Virus types 1 and 2.
Journal of histotechnology
Lloyd J,Copaciu R,Yahyabeik A,DeWit C,Cummings K,Lacey M,Su Q
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Sun Dec 01 00:00:00 EST 2019
Influence of Xiaoyaosan on depressive-like behaviors in chronic stress-depressed rats through regulating tryptophan metabolism in hippocampus.
Neuropsychiatric disease and treatment
Jiao H,Yan Z,Ma Q,Li X,Jiang Y,Liu Y,Chen J
MA1-140 was used in Western Blotting to establish a depression rat model by the chronic immobilisation stress method and observe the change in tryptophan metabolism in hippocampus and the effects of Xiaoyaosan.
Wed Mar 30 00:00:00 EDT 2022
Allograft inflammatory factor-1 supports macrophage survival and efferocytosis and limits necrosis in atherosclerotic plaques.
Atherosclerosis
Egaña-Gorroño L,Chinnasamy P,Casimiro I,Almonte VM,Parikh D,Oliveira-Paula GH,Jayakumar S,Law C,Riascos-Bernal DF,Sibinga NES
MA1-140 was used in Western Blotting to characterize Allograft inflammatory factor-1 (AIF1) as a positive regulator of the NF-κB pathway that supports monocyte/macrophage functions such as survival and efferocytosis.
Tue Oct 01 00:00:00 EDT 2019
An ANGPTL4-ceramide-protein kinase Cζ axis mediates chronic glucocorticoid exposure-induced hepatic steatosis and hypertriglyceridemia in mice.
The Journal of biological chemistry
Chen TC,Lee RA,Tsai SL,Kanamaluru D,Gray NE,Yiv N,Cheang RT,Tan JH,Lee JY,Fitch MD,Hellerstein MK,Wang JC
MA1-140 was used in Western Blotting to indicate lipid disorders may be influenced by induced hepatic de novo lipogenesis as a result of chronic dexamethasone treatment.
Fri Jun 07 00:00:00 EDT 2019
Targeted Protein Degradation through Cytosolic Delivery of Monobody Binders Using Bacterial Toxins.
ACS chemical biology
Schmit NE,Neopane K,Hantschel O
MA1-140 was used in Western Blotting to provide a prime example of the delivery of a stoichiometric protein inhibitor of an endogenous target protein to cells and inducing its degradation without the need of genetic manipulation of target cells.
Fri May 17 00:00:00 EDT 2019
Neuroprotective potential of ketamine prevents developing brain structure impairment and alteration of neurocognitive function induced via isoflurane through the PI3K/AKT/GSK-3β pathway.
Drug design, development and therapy
Wang R,Zhang Z,Kumar M,Xu G,Zhang M
MA1-140 was used in Western Blotting to conclude that ketamine prevented the cognitive impairment induced by isoflurane anesthesia through anti-apoptotic, anti-inflammatory, and antioxidant effects via the PI3K/AKT/GSK-3Β pathway.
Fri Aug 09 00:00:00 EDT 2019
Preventive Effects of Different Fermentation Times of Shuidouchi on Diphenoxylate-Induced Constipation in Mice.
Foods (Basel, Switzerland)
Chen L,Zhang J,Suo H,Wang W,Wang H,Zhang Y,Hu Q,Zhao X,Li J
MA1-140 was used in Western Blotting to compare the prevention effects of Shuidouchi with different fermentation times on constipation in mice.
Fri Mar 01 00:00:00 EST 2019
Hypoxia modulates the stem cell population and induces EMT in the MCF-10A breast epithelial cell line.
Oncology reports
Daly CS,Flemban A,Shafei M,Conway ME,Qualtrough D,Dean SJ
Published figure using beta Actin monoclonal antibody (Product # MA1-140) in Western Blot
Thu Feb 01 00:00:00 EST 2018
CRISPR/Cas9‑mediated hypoxia inducible factor‑1α knockout enhances the antitumor effect of transarterial embolization in hepatocellular carcinoma.
Oncology reports
Liu Q,Fan D,Adah D,Wu Z,Liu R,Yan QT,Zhang Y,Du ZY,Wang D,Li Y,Bao SY,Liu LP
MA1-140 was used in Western Blotting to study the therapeutic potential of HIF-1α as a knockout target in the treatment of hepatocellular carcinoma.
Thu Nov 01 00:00:00 EDT 2018
Lactobacillus casei Strain Shirota Enhances the In Vitro Antiproliferative Effect of Geniposide in Human Oral Squamous Carcinoma HSC-3 Cells.
Molecules (Basel, Switzerland)
Qian Y,Song JL,Sun P,Yi R,Liu H,Feng X,Park KY,Zhao X
MA1-140 was used in Western Blotting to investigate the enhanced anti-proliferative effect of Lactobacillus casei strain Shirota on geniposide actions in human oral squamous carcinoma HSC-3 cells.
Thu May 03 00:00:00 EDT 2018
Proteomic analysis of exosomes derived from human lymphoma cells.
European journal of medical research
Yao Y,Wei W,Sun J,Chen L,Deng X,Ma L,Hao S
MA1-140 was used in western blot to characterize the proteomic content of lymphoma cell-derived exosomes.
Thu Jan 29 00:00:00 EST 2015
