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PA1-21477 detects beta Galactosidase in E. coli samples.
PA1-21477 has been successfully used in ELISA, immunocytochemistry, immunofluorescence, immunohistochemistry (frozen and FFPE), immunoprecipitation, dot blot and Western blot procedures.
The PA1-21477 immunogen corresponds to recombinant full length beta Galactosidase protein expressed in E. coli.
Store at 4ºC short term. For extended storage, store at -20ºC, avoiding freeze/thaw cycles.
Beta Galactosidase encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene have been associated with GM1-gangliosidosis and Morquio B syndrome. Diseases associated with GLB1 include Gm1-Gangliosidosis, Type I and Gm1-Gangliosidosis, Type Ii.
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