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eIF4G3 Antibody (PA5-31101) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of eIF4G3 was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Green: eIF4G3 Polyclonal Antibody (Product # PA5-31101) diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
产品信息
PA5-31101
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein fragment corresponding to a region within amino acids 1 and 203 of Human EIF4G3
偶联物
形式
Liquid
浓度
0.26 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548575
产品详细信息
Recommended positive controls: 293T, A431, HeLa, HepG2, mouse testis.
Predicted reactivity: Human (99%), Mouse (96%), Rat (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: eIF-4-gamma 3; eIF-4-gamma II; eIF-4G 3; eIF4G 3; eIF4GII; Eukaryotic translation initiation factor 4 gamma 3; RP11-190H11.1
基因别名: 1500002J22Rik; 4833436O05; 4930523M17Rik; eIF-4G 3; eIF4G 3; EIF4G3; eIF4GII; G1-419-52; repro8
UniProt ID: (Human) O43432, (Mouse) Q80XI3
Entrez Gene ID: (Human) 8672, (Mouse) 230861, (Rat) 298573
