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Invitrogen
gamma Adaptin Recombinant Rabbit Monoclonal Antibody (23GB3655)
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 4
gamma Adaptin Antibody (MA5-53632) in ICC/IF
Immunocytochemistry analysis of gamma Adaptin in HepG2 cells. Nuclei were stained blue with DAPI; gamma Adaptin recombinant monoclonal antibody (Product # MA5-53632) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
产品信息
MA5-53632
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
23GB3655
抗原
A synthetic peptide of human AP1G1 (780-822AA).
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
靶标信息
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adapter-related protein complex 1 subunit gamma-1; adaptor protein complex AP-1 gamma 1 subunit; Adaptor protein complex AP-1 subunit gamma-1; adaptor protein complex AP-1, gamma 1 subunit; adaptor-related protein complex 1 gamma 1 subunit; Adaptor-related protein complex 1 subunit gamma-1; adaptor-related protein complex 1, gamma 1 subunit; AP-1 complex subunit gamma-1; clathrin assembly protein complex 1 gamma large chain; Clathrin assembly protein complex 1 gamma-1 large chain; clathrin-associated/assembly/adaptor protein, large, gamma 1; gamma adaptin; Gamma-adaptin; Gamma1-adaptin; golgi adaptor HA1/AP1 adaptin gamma subunit; Golgi adaptor HA1/AP1 adaptin subunit gamma-1; MGC18255; testicular tissue protein Li 21
基因别名: AA409002; ADTG; AP1G1; AU041323; AW551707; CLAPG1; D8Ertd374e
UniProt ID: (Human) O43747, (Mouse) P22892
Entrez Gene ID: (Human) 164, (Mouse) 11765, (Rat) 171494
intracellular protein transport
antigen processing and presentation of exogenous peptide antigen via MHC class II
melanosome organization
endosome to melanosome transport
positive regulation of natural killer cell degranulation
positive regulation of natural killer cell mediated cytotoxicity
regulation of defense response to virus by virus
Golgi to lysosome transport
microtubule cytoskeleton organization
transport
protein transport
vesicle-mediated transport
