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mGluR5 (extracellular) Antibody (PA5-77416) in ICC/IF
Immunocytochemistry analysis of mGluR5 (extracellular) in rat pituitary cells. Samples were probed with mGluR5 (extracellular) polyclonal antibody (Product # PA5-77416) at a dilution of 1:100, and incubated with goat anti-rabbit-AlexaFluor-555.
产品信息
PA5-77416
产品规格
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide EGFAQENSKYNKTC, corresponding to amino acids 367-380 of rat mGluR5
偶联物
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2736146
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
靶标信息
GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
