Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
OSM00019A-100UG
应用
建议稀释比
已发表文章
产品规格
种属反应
Rat
已发表种属
Not Applicable
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
MC192
抗原
Nerve growth factor receptor (TNFR superfamily, member 16)
偶联物
形式
Lyophilized
纯化类型
Affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: rat p75NTR.
靶标信息
Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CD271; CD271 antigen; Gp80-LNGFR; low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; Low-affinity nerve growth factor receptor p75NGFR; Low-affinity nerve growth factor receptor p75NGR; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; p-75; p75 ICD; p75 ntr; TNR16; Tumor necrosis factor receptor superfamily member 16
基因别名: LNGFR; Ngfr; p75; p75NTR; RNNGFRR; Tnfrsf16
UniProt ID: (Rat) P07174
Entrez Gene ID: (Rat) 24596
intracellular protein transport
apoptotic process
signal transduction
axon guidance
central nervous system development
response to wounding
regulation of gene expression
positive regulation of cell death
negative regulation of neuron projection development
programmed cell death
detection of temperature stimulus
sensory perception of pain
nerve development
hair follicle morphogenesis
positive regulation of myelination
positive regulation of synaptic transmission, cholinergic
response to lipopolysaccharide
circadian regulation of gene expression
cellular response to oxidative stress
positive regulation of Rho protein signal transduction
skeletal muscle cell differentiation
negative regulation of fibroblast growth factor receptor signaling pathway
positive regulation of odontogenesis of dentin-containing tooth
glucose homeostasis
positive regulation of apoptotic process
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
skin development
positive regulation of fibroblast proliferation
negative regulation of hair follicle development
positive regulation of protein kinase B signaling
negative regulation of mitochondrial depolarization
positive regulation of synaptic transmission, glutamatergic
negative regulation of cell death
positive regulation of neuron death
regulation of reactive oxygen species metabolic process
positive regulation of apoptotic signaling pathway
regulation of glucose import in response to insulin stimulus
