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Human C1qTNF1 quantitates human C1qTNF1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human C1qTNF1.
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : C1QTNF1, CTRP1, GIP, UNQ310/PRO353, ZSIG37
基因ID : (Human) 114897
基因符号 : C1QTNF1
蛋白别名 : Complement C1q tumor necrosis factor-related protein 1, G protein coupled receptor interacting protein, G protein-coupled receptor-interacting protein, GIP
UniProt ID (Human) Q9BXJ1