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Human CFHR1 quantitates human CFHR1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CFHR1.
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CFHL, CFHL1, CFHL1P, CFHR1, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2
基因ID : (Human) 3078
基因符号 : CFHR1
蛋白别名 : complement factor H-related 1 pseudogene, Complement factor H-related protein 1, FHL-1, FHR-1, H factor (complement)-like 1, H factor (complement)-like 2, H factor-like protein 1, H-factor-like 1, H36
UniProt ID (Human) Q03591