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Human CXCL-17 quantitates human CXCL-17 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CXCL-17.
CXCL17 is a chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. In particular, CXCL17 is a mucosal chemokine that attracts dendritic cells and blood monocytes to the lungs. CXCL17 plays a role in angiogenesis and possibly in the development of tumors. Further, CXCL17 acts as an anti-inflammatory in the stomach and may play a role in the innate defense against infections. CXCL17 also activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17 seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. Diseases associated with CXCL17 dysfunction include cholera.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CXCL17, Dcip1, DMC, UNQ473, UNQ473/PRO842, VCC-1, VCC1
基因ID : (Human) 284340
基因符号 : CXCL17
蛋白别名 : 6-Cys CXCL17, C-X-C motif chemokine 17, chemokine (C-X-C motif) ligand 17, Dendritic cell and monocyte chemokine-like protein, DMC, VEGF co-regulated chemokine 1, VEGF coregulated chemokine 1
UniProt ID (Human) Q6UXB2