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Human Chitotriosidase quantitates human Chitotriosidase in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Chitotriosidase.
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CHI3, CHIT, CHIT1, CHITD
基因ID : (Human) 1118
基因符号 : CHIT1
蛋白别名 : chitinase 1 (chitotriosidase), Chitinase-1, Chitotriosidase-1, plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
UniProt ID (Human) Q13231