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Human Dectin-1 Kit quantitates human Dectin-1 Kit in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Dectin-1 Kit.
CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : BGR, CANDF4, CD369, CLEC7A, CLECSF12, DECTIN1, SCARE2, UNQ539/PRO1082
基因ID : (Human) 64581
基因符号 : CLEC7A
蛋白别名 : Beta-glucan receptor, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12, C-type lectin domain family 7 member A, C-type lectin domain family 7, member A, C-type lectin superfamily member 12, CD369, DC-associated C-type lectin 1, dectin-1, Dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, lectin-like receptor 1
UniProt ID (Human) Q9BXN2