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The Human Eotaxin 2/CCL24 ELISA quantitates Hu Eotaxin-2 in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu Eotaxin-2.
原理方法
The Human Eotaxin-2 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CCL24, Ckb-6, MPIF-2, MPIF2, SCYA24
基因ID : (Human) 6369
基因符号 : CCL24
蛋白别名 : C-C motif chemokine 24, chemokine (C-C motif) ligand 24, CK-beta-6, Eosinophil chemotactic protein 2, Eotaxin-2, MPIF-2, Myeloid progenitor inhibitory factor 2, small inducible cytokine subfamily A (Cys-Cys), member 24, Small-inducible cytokine A24
UniProt ID (Human) O00175