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Human Ficolin-3 quantitates human Ficolin-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Ficolin-3.
H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : FCN3, FCNH, HAKA1
基因ID : (Human) 8547
基因符号 : FCN3
蛋白别名 : Collagen/fibrinogen domain-containing lectin 3 p35, Collagen/fibrinogen domain-containing protein 3, Ficolin-3, Hakata antigen
UniProt ID (Human) O75636