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The Human Growth Regulated Oncogene Beta (GROB/CXCL2) ELISA quantitates GROB/CXCL2 in serum, plasma, and other biological fluids
The Human GROB/CXCL2 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the binding of the second (detector) antibody to the target on a different epitope from the capture antibody. An antibody conjugated with enzyme binds the formed sandwich. After incubation and washing steps to rid the microplate of unbound substances, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
Rigorous validation:
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CINC-2a, CXCL2, GRO2, GROB, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2
基因ID : (Human) 2920
基因符号 : CXCL2
蛋白别名 : C-X-C motif chemokine 2, chemokine (C-X-C motif) ligand 2, Gro-beta, GRO2 oncogene, Growth-regulated protein beta, Macrophage inflammatory protein 2-alpha, melanoma growth stimulatory activity beta, MGSA beta, MIP2-alpha
UniProt ID (Human) P19875