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The Human Insulin-like Growth Factor Binding Protein 6 (Hu IGFBP6) ELISA quantitates Hu IGFBP6 in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu IGFBP6.
原理方法
The Human IGFBP6 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6, which specifically inhibits IGF-II actions, is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : IBP6, IGFBP6
基因ID : (Human) 3489
基因符号 : IGFBP6
蛋白别名 : IBP-6, IGF-binding protein 6, IGFBP-6, IGF binding protein 6, insulin-like growth factor binding protein 6, Insulin-like growth factor-binding protein 6
UniProt ID (Human) P24592