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产品规格
检测灵敏度
Lot-specific
测定范围
Lot-specific
手工操作时间
1 hr 45 min
总时间
24 hr 30 min
均相（无需洗涤）
No
检测仪器
Colorimetric Microplate Reader
产品规格
10 x 96 Tests
产品成分
This Human/Mouse/Rat BMP-2 ELISA Kit includes Capture Antibody, Detection Antibody, Protein Standard, and HRP-conjugate. The HRP-conjugate is packaged separately.
储存
Refer to product documentation for component specific storage temperature.
蛋白名称
BMP-2
蛋白家族
Growth Factors & Receptors
均相（无需洗涤）
Human, Mouse, Rat
检测试剂盒格式
ELISA Development Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
900-T255K consists of: 900-T255 (capture antibody, detection antibody, and protein standard), and HRP-17UL (streptavidin HRP-conjugate).
Human/Mouse/Rat BMP-2 TMB ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinant human/mouse/rat BMP-2 in a sandwich ELISA format. Human/Mouse/Rat BMP-2 TMB ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells.
The TMB ELISA Buffer Kit (Product # 900-T00), sold separately, is recommended to be used in conjunction with this TMB ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.
靶标信息
Bone Morphogenic Proteins (BMP) are members of the TGF-beta superfamily that affect bone and cartilage formation (Hogan 1996, Reddi 1998 and Francis-West et al. 1999). Mature BMPs are 30-38 kDa proteins that assume a TGF-beta -like cysteine knot configuration. Lovostatin increases bone formation by turning on the bmp-2 gene (Mundy et al. 1999). BMPs stimulate the production of specific bone matrix proteins and alter stromal cell and osteoclast proliferation (Macias et al. 1999, Lecanda et al. 1997). BMPs may also be an important factor for development of the viscera, with roles in cell proliferation, apoptosis, differentiation, and morphogenesis (Hogan 1996, Dale and Wardle 1999). BMPs appear to be responsible for normal dorsal/ventral patterning. Like TGF-beta, BMPs bind to a type II receptor, which then recruits the transducing type I receptor unit, activating the Smad protein signaling pathway (Massague 1994, Derynck 1997, Attisano 1993).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : AI467020, BDA2, Bmp-2, BMP2, BMP2A
基因ID : (Human) 650, (Mouse) 12156, (Rat) 29373
基因符号 : BMP2, Bmp2, Bmp2
蛋白别名 : BMP-2, BMP-2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A
UniProt ID (Human) P12643, (Mouse) P21274, (Rat) P49001
