Search Thermo Fisher Scientific
Human OX40L quantitates human OX40L in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human OX40L.
The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CD134L, CD252, GP34, OX-40L, OX4OL, TNFSF4, TNLG2B, TXGP1
基因ID : (Human) 7292
基因符号 : TNFSF4
蛋白别名 : CD134 ligand, CD252, Glycoprotein Gp34, OX40 antigen ligand, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, tax-transcriptionally activated glycoprotein 1 (34kD), tumor necrosis factor (ligand) superfamily member 4, tumor necrosis factor ligand 2B, Tumor necrosis factor ligand superfamily member 4
UniProt ID (Human) P23510