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Human PTH1R quantitates human PTH1R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PTH1R.
Parathyroid hormone receptor 1 is a member of the G-protein coupled receptor family. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Parathyroid hormone receptor 1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : PFE, PTH1R, PTHR, PTHR1
基因ID : (Human) 5745
基因符号 : PTH1R
蛋白别名 : Parathyroid hormone 1 receptor, parathyroid hormone receptor 1, Parathyroid hormone/parathyroid hormone-related peptide receptor, parathyroid hormone/parathyroid hormone-related protein receptor, PTH/PTHr receptor, PTH/PTHrP type I receptor, PTH1 receptor, seven transmembrane helix receptor
UniProt ID (Human) Q03431