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Human Serpin A3/Alpha-1-Antichymotrypsin quantitates human Serpin A3/Alpha-1-Antichymotrypsin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Serpin A3/Alpha-1-Antichymotrypsin.
SERPINA encodes Alpha 1-ACT. It is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : AACT, ACT, GIG24, GIG25, SERPINA3
基因ID : (Human) 12
基因符号 : SERPINA3
蛋白别名 : ACT, Alpha-1-antichymotrypsin, Cell growth-inhibiting gene 24/25 protein, growth-inhibiting protein 24, growth-inhibiting protein 25, serine (or cysteine) proteinase inhibitor, clade A, member 3, Serpin A3, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
UniProt ID (Human) P01011