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产品规格
检测灵敏度
2 ng/mL
测定范围
2-500 ng/mL
检测样本类型/体积
{Serum=50 µL, Supernatant=50 µL, Plasma=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Colorimetric Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
2-8°C
蛋白名称
TPSB2
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human Tryptase beta-2/TPSB2 quantitates human Tryptase beta-2/TPSB2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Tryptase beta-2/TPSB2.
靶标信息
TPSB2 is a protein coding gene. Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : TPS2, TPSB2, tryptaseB, tryptaseC
基因ID : (Human) 64499
基因符号 : TPSB2
蛋白别名 : mast cell tryptase beta II, mast cell tryptase beta III, testicular tissue protein Li 163, Tryptase beta-2, Tryptase II, Tryptase-2
UniProt ID (Human) P20231
