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Rat TWEAK R quantitates rat TWEAK R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat TWEAK R.
TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in demonstrate that this relatively small molecule is a fully transformed cell lines. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library. TweakR is a small protein belonging to TNF receptor super family. TweakR is capable of intiating a proliferative signal by binding to TRAF1, 2, and 3. TweakR mRNA is upregulated during tissue regeneration in the aorta and liver. It may also play a role in vascular cell migration and angiogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : Fn14
基因ID : (Rat) 302965
基因符号 : Tnfrsf12a
蛋白别名 : tumor necrosis factor receptor superfamily member 12A