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Rat GDNF quantitates rat GDNF in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat GDNF.
GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : Gdnf, gndf
基因ID : (Rat) 25453
基因符号 : Gdnf
蛋白别名 : Astrocyte-derived trophic factor, ATF, glial cell line derived neurotrophic factor, Glial cell line derived neutrophic factor, Glial cell line-derived neurotrophic factor
UniProt ID (Rat) Q07731