Aquilos 2 Cryo-FIB

Dedicated cryo-FIB microscope to prepare cryo-lamellas for cryo-electron tomography

The Thermo Scientific Aquilos 2 Cryo-FIB is dedicated to the preparation of thin, electron-transparent lamellas for high-resolution cellular cryo-electron tomography or MicroED of micro-crystals.  With the Aquilos 2 Cryo-FIB, you can automate steps in the workflow to produce multiple lamellas from specific programmed locations. The improved dedicated cryo-hardware provides longer run times at ultra-low contamination rates. 

Instrument features

Automated batch cryo-lamella milling

Explore state-of-the-art automation for cryo-lamella production and work with challenging bulk-frozen samples that require cryo-lift-out sample preparation.

'On-the-grid’ in situ lamella prepared with the Aquilos Cryo-FIB

Correlative fluorescence and electron imaging in one system

The iFLM Correlative System (Integrative Fluorescence Light Microscope) allows you to combine fluorescence imaging and ion milling within a single cryo-FIB SEM microscope.

Localization of fluorescent targets inside the Aquilos Cryo-FIB vacuum chamber.

Aquilos Cryo-FIB resources

Learn more from scientists who are using the Aquilos Cryo-FIB and take a closer look with on-demand webinars and videos.

Thermo Scientific Aquilos 2 Cryo-FIB

Cryo-FIB for your lab

Choose the best cryo-focused-ion-beam (cryo-FIB) for your laboratory.  Learn more about other microscope models.

Thermo Scientific Cryo-FIB microscopes

Cryo-ET service and support

To ensure optimal system performance, we provide you access to a world-class network of field service experts, technical support, and workflow validation. 

Cryo ET data acquisition

Explore cryo-electron tomography

The Thermo Scientific cryo-electron tomography (cryo-ET) workflow is a complete end-to-end workflow covering cell culture to flash freezing cells to final 3D visualization and analysis.

Cryo electron tomography data for the golgi

For Research Use Only. Not for use in diagnostic procedures.

1x1 image pixel for data collection