The dynamic and flexible nature of biomolecules poses a major challenge for structural biologists. Thus, the full characterization of a macromolecular system requires the combination of many structure-determination techniques, an approach known as integrative structural biology.

In this context, advances in mass spectrometry (MS) techniques in combination with cryo-electron microscopy (cryo-EM) and other structural tools is revolutionizing the understanding of protein structure, function and dynamics.

Download this eBook to learn more about:

  • Tools for integrative structural biology
  • Combining cryo-EM, cryo-ET and mass spectrometry
  • The benefits of integrated modeling

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