Microarray Analysis Instruments for Population Genomics

Research with trusted results—gain new insights using cost-effective microarray technology

Population genomics turns data into health insights. Increasingly, genotyping data from diverse populations around the globe are complementing the European and Caucasian data that have long dominated biobanks and genetic databases.

The Applied Biosystems GeneTitan MC Fast Scan Instrument provides the highest throughput and laboratory productivity per technician by minimizing user intervention and allowing unattended, overnight processing of large numbers of samples in parallel. This unique degree of hands-off automation means your data will be consistently reproducible while maximizing productivity.

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GeneTitan MC Fast Scan Instrument

The GeneTitan MC Fast Scan Instrument and proven Axiom array plates in 96- and 384-array layouts are the first to provide a hands-free, automated solution for genome-wide SNP genotyping.

The GeneTitan MC Fast Scan Instrument automates array processing from target hybridization to data generation by combining a hybridization oven, fluidics processing, and state-of-the art imaging device into a single bench-top instrument.

The imaging device in the GeneTitan MC Fast Scan Instrument uses an external, high-intensity xenon lamp and dual excitation and emission filters to capture images from array plates for use in genotyping and microbiome studies.

Key benefits include:

Fast—condenses hands-on processing time to as little as 30 minutes, images an array in less than five minutes, and operates unattended overnight
Scalable—meets both medium- and high-throughput needs, enables fast time to data, and requires minimal manual intervention
Flexible—supports genotyping studies on multiple array plate formats
Accurate—enables high-quality, consistent data by processing multiple samples under identical conditions
Adaptable—creates flexible workflows and sample registration via GeneChip Command Console Software

GeneChip Command Console Software

GeneChip Command Console Software provides customization, automation, and integration flexibility along with full-range support:

Provides summary of probe cell intensity data (CEL file generation); enables sample and array registration, data management, instrument control, and automatic and manual image gridding
Enables flexiblility to customize, automate, and integrate workflows with a variety of laboratory information management systems
Supports the full range of assays by enabling seamless integration with downstream primary analysis applications such as Axiom Analysis Suite and Transcriptome Analysis Console (TAC) Software

NIMBUS Target Preparation Instrument

We have partnered with Hamilton Robotics to provide you with the latest in ultra-compact and precision-based liquid-handling instrumentation. The NIMBUS Target Preparation Instrument is industry-recognized for its high-end manufacturing and superior pipetting performance at an affordable price.

We have automated the target preparation steps for the Axiom 2.0 assay, including DNA amplification, fragmentation, purification, resuspension, hybridization preparation, and stain preparation for the GeneTitan MC Instrument.

Axiom target preparation on the automated liquid-handling workstation helps minimize run-to-run variability and the labor burden associated with complex manual pipetting, helping to improve test reproducibility and laboratory efficiency.

Target preparation for Axiom genotyping is now effortless with Axiom 96-sample automated target preparation, which offers:

Small footprint, sleek design, and industry-recognized engineering
Advanced pipetting technology for precise yet flexible liquid handling
Workflow designed to accommodate 96 samples
Laptop with easy-to-use software interface including visual cues for each assay step

The NIMBUS Target Preparation Instrument represents the latest in compact, high-speed automated multi-channel pipetting. It features a 1-mL 96-channel multi-pipetting head for plate-based pipetting using a combination of capacitance-based liquid level detection and pressure-based liquid level detection for unparalleled performance.

The NIMBUS Target Preparation Instrument, co-developed with Hamilton Robotics, features an automation deck optimized for use with the Axiom assay protocol and an automated workflow that is compatible with Axiom 2.0 reagent kits. The on-deck thermoshake cooling block and customized trash chute provide convenience and support for assay robustness. The compact size allows the flexibility to place the instrument on virtually any bench top.

The NIMBUS Target Preparation Instrument is provided with a Dell™ laptop computer that is powered by an easy-to-use interface. The high-resolution visual display and simple on-screen instructions provide simple visual cues throughout assay progression.

Learn more about our NIMBUS target preparation instrument

Product specifications

GeneTitan MC Fast Scan Instrument	Nimbus Target Preparation Instrument
Dimensions
55” W x 33” D x 26” H (139.7 cm W x 83.82 cm D x 66 cm H)	20.1 in. W x 37.4 in. L x 30.3 in. Maximum H (20.1 x 37.4 x 30.3 inches)
Applications
Genome-Wide Association Study, polygenic risk scores, pharmacogenomics, general population-scale genotyping, blood typing, agrigenomics, carrier screening, custom arrays	Post-PCR automated target preparation
Weight
147 kg	58.9 kg