SeqStudio Genetic Analyzer

Simple, fast, low-throughput Sanger sequencing and fragment analysis system

The Applied Biosystems SeqStudio Genetic Analyzer is a low-throughput, easy-to-use, and convenient benchtop system that delivers gold-standard Sanger sequencing technology and fragment analysis by capillary electrophoresis with a simple click. Just load your samples, click in the innovative all-in-one cartridge, and go.

 

The SeqStudio instrument is easy to use across a broad range of applications, including de novo, targeted, and plasmid Sanger sequencing, CRISPR-Cas9 genome editing confirmation, cell line authentication, and detection of single nucleotide polymorphisms (SNPs). Setup is simple and you will be ready to go in minutes. The SeqStudio Genetic Analyzer offers data quality, usability, service, and support at an affordable price.

 

Need higher throughput? Like the SeqStudio instrument, our  SeqStudio Flex Genetic Analyzer is an easy-to-use, flexible system for Sanger sequencing and fragment analysis, but with higher throughput.

SeqStudio 3D Tour

Features

The SeqStudio Genetic Analyzer is designed for both new and experienced users who need simple and affordable Sanger sequencing and fragment analysis, without compromising performance or quality.

Innovative all-in-one cartridge

Just load your samples, insert the cartridge, and go— no need for technical experts for set-up or maintenance

Fast turnaround

Complete your run in as little as 30 minutes

Optimized end-to-end workflow

Single polymer system allows for Sanger sequencing and fragment analysis samples to be run on the same plate in the same workflow with no reconfiguration

Touchscreen usability

The intuitive touchscreen interface simplifies plate, sample, and run setup and displays results in a choice of formats

Connectivity with Thermo Fisher Connect

Manage your run anytime, anywhere from Thermo Fisher Scientific’s Connect cloud-based platform

Comprehensive analysis software

Primary and secondary analysis software modules are available for download or through Thermo Fisher Connect

Traceability and data security module

Optional security, audit, and electronic signature (SAE) software module offers an electronic data chain of custody to help ensure integrity of your data

SmartStart customer orientation

Every SeqStudio instrument purchase includes a one-day, on-site SmartStart Orientation training course to get you up and running quickly

Learn more about these features:

Applications

Sanger sequencing is the gold standard for sequencing technology, enabling a high degree of accuracy, long-read capability, and the flexibility to support a diverse range of applications in many research areas. Similarly, analysis of DNA fragments enables a multitude of applications, from genotyping to bacteria identification and from plant screening to gene expression profiling.

 

Below are examples of applications that can be run on the SeqStudio Genetic Analyzer. For more application information, see our SeqStudio Applications page.

 

De novo Sanger sequencing

Targeted Sanger sequencing

Plasmid sequencing

Oncology research

Microbial species identification

Next-generation sequencing (NGS) confirmation

CRISPR-Cas9 genome editing analysis

Human cell line authentication

Single-nucleotide polymorphism (SNP) genotyping

Analysis of human copy number variation (CNV)

DNA methylation analysis

Low-level somatic variant detection and analysis

Microsatellite instability (MSI) analysis

Repeat DNA expansion

SARS-CoV-2 identification

 

Learn more about these applications:

Optimized end-to-end workflow

The SeqStudio Genetic Analyzer can perform both Sanger sequencing and fragment analysis runs on the same plate within the same workflow. Gain flexibility in your laboratory schedule and help maximize your time by removing the need to batch samples.

Dual workflow.

The SeqStudio Genetic Analyzer can perform simultaneous Sanger sequencing and fragment analysis runs on the same plate.

Analysis of cell line contamination on the SeqStudio Genetic Analyzer.

We offer a complete product portfolio for every step of the Sanger sequencing and fragment analysis workflows. For Sanger sequencing, this includes amplifying the DNA template, PCR cleanup, cycle sequencing, sequencing cleanup, on‑instrument consumables, and data analysis. For fragment analysis, this includes DNA extraction, PCR amplification, on‑instrument consumables, and data analysis.

Videos, webinars, and demos

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The Applied Biosystems SeqStudio Genetic Analyzer production unveiling

The Applied Biosystems SeqStudio Genetic Analyzer is here. Sanger sequencing and fragment analysis on one plate with just one click. Watch the unveiling.
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SeqStudio Genetic Analyzer product demo

See how easy it is to load your samples, click in the cartridge, and go. Set up and monitor your run on the instrument or remotely—even on your phone.
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Introduction to SeqStudio Applications

In this 30-minute talk, find out how the new Applied Biosystems SeqStudio Genetic Analyzer enables Sanger sequencing and fragment analysis for applications.
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Fast results, more answers, one run with the easy-to-use Applied Biosystems SeqStudio Genetic Analyzer

The unique all-in-one cartridge-based system makes the Applied Biosystems SeqStudio Genetic Analyzer convenient and easy to use.
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First impressions with the Applied Biosystems SeqStudio Genetic Analyzer

Four labs from all corners of the globe had a chance to experience the Applied Biosystems SeqStudio Genetic Analyzer before anyone else. Thermo Fisher Scientific camera crews captured their first impressions on this new way of doing Sanger sequencing.

Specifications

Attribute

Description

Number of capillaries

4

Number of dyes

6

Sample format

96-well standard plate and standard 8-tube strips

Applications
  • Sanger sequencing (resequencing NGS confirmation, indels, heterozygote detection, minor variant detection, microbial identification, genome editing validation)
  • Fragment analysis (microsatellite analysis, compatible with MLPA, Applied Biosystems SNaPshot applications, cell line authentication

Secondary analysis software included
  • Sequence Analysis Software
  • SeqScape Software
  • Variant Reporter Software
  • GeneMapper Software
  • Minor Variant Finder Software
  • Sequencing Analysis Modules (Quality Check, Variant Analysis, and Next-Generation Confirmation) on Connect platform
  • Fragment Analysis Modules (Peak Scanner and Microsatellite Analysis) on Connect platform
  • SeqScreener Gene Editing App

Warranty

Included (1 year)

In-lab application training

Included

Services

Superior services and support for the SeqStudio Genetic Analyzer

Choose a service plan that’s right for you. Help maximize system uptime, reduce repair costs and turnaround time, extend the life of your instrument, and help keep it running at peak performance with one of our comprehensive service plans. Choose from a variety of service options that balance your budget, productivity, uptime, and regulatory requirements. When it comes to superior services and support for your SeqStudio Genetic Analyzer, we’ve got your back.

 

SmartStart Orientation enables your success

Every SeqStudio Genetic Analyzer includes a one-day, on-site SmartStart Orientation to get you up and running quickly. Led by a field applications scientist (FAS) at your location, this interactive training provides an overview of instrument operation and maintenance, data collection and analysis software, cloud connectivity, data troubleshooting, and more.

 

Comprehensive warranty and service plans protect your investment

SeqStudio Genetic Analyzers are protected by a standard one-year factory warranty that covers necessary costs for travel, labor, and parts. Extended-coverage service plans are available at the time of instrument purchase. Keep your laboratory running smoothly with preventive maintenance, proactive instrument monitoring, and fast response time that’s included with one of our superior service plans.

 

Service plan overview

Service aspect

AB Maintenance (Plus) plan

AB Assurance plan

AB Complete plan

On-site response time

Target 2 business days*

Guaranteed 2 business days*

Guaranteed next business day*

Scheduled on-site planned maintenance

✓

✓

✓

Remote instrument diagnostics

✓

✓

✓

Parts, labor, and travel

10% discount (US only)

✓

✓

Priority access to remote service engineer

 

✓

✓

Requalification, post-planned maintenance (PM) and critical repairs

 

 

✓

Troubleshooting by field application scientist

 

 

✓

*Response times vary by region

 

All service plans include scheduled planned maintenance and the latest software updates, enabling optimum reliability. Service plans help keep operating costs predictable, as parts, labor, and engineer travel are included or discounted.

Qualification services help ensure regulatory compliance

Instrument hardware qualifications for SeqStudio Genetic Analyzers include installation qualification (IQ), operational qualification (OQ), and instrument performance verification (IPV) services. Our qualification specialists will partner with you to deliver timely, cost-effective, and trusted qualification services that include reliable, audit-style documentation to help ensure your SeqStudio Genetic Analyzer meets regulatory requirements.

Resources

Ordering information

For Research Use Only. Not for use in diagnostic procedures.