Invitrogen

Bovine Factor X Native Protein

说明书

技术支持

说明书

技术支持

产品信息

RP-43073

应用

建议稀释比

已发表文章

对照试剂 (Ctrl)

Assay-dependent

产品规格

种属

Bovine

分子量

55.1 kDa

分类

Native

类型

Protein

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

6.0 mg/mL

纯化类型

purified

保存液

50% water with 50% glycerol

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

产品详细信息

RP-43073 contains native bovine Factor X protein.

RP-43073 may be used as a positive control in many immunological assays.

靶标信息

F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。