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产品信息
RP-90030
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
ALILESPFTNIREEAKSHPFSVIYRYFPGFDWFFLDPITSSGIKFANDENVKHISCPLLILHAEDDPVVPFQLGRKLYSIAAPARSFRDFKVQFVPFHSDLGYRHKYIYKSPELPRILRP
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55445. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol, the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC, resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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生物信息学
蛋白别名: 2-arachidonoylglycerol hydrolase; 2-arachidonoylglycerol hydrolase ABHD12; Abhydrolase domain-containing protein 12; DKFZP434P106; hABHD12; Lysophosphatidylserine lipase ABHD12; Monoacylglycerol lipase ABHD12; Oxidized phosphatidylserine lipase ABHD12
基因别名: ABHD12; ABHD12A; BEM46L2; C20orf22; dJ965G21.2; PHARC
UniProt ID: (Human) Q8N2K0
Entrez Gene ID: (Human) 26090
