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Highest antigen sequence indentity to the following orthologs: Mouse (60%), Rat (60%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-110991. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Abelson interactor 1; Abi-1; Abl interactor 1; Abl-binding protein 4; abl-interactor 1; Abl-interactor protein 1 long; AblBP4; e3B1; EL2; Eps8 SH3 domain-binding protein; Eps8-binding protein; HS3; interactor protein AblBP4; nap1 binding protein; Nap1-binding protein; Nap1BP; Spectrin SH3 domain-binding protein 1; SPH3; SPTA
基因别名: ABI-1; ABI1; ABLBP4; E3B1; NAP1BP; SSH3BP; SSH3BP1
UniProt ID: (Human) Q8IZP0
Entrez Gene ID: (Human) 10006