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Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58649. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon. [provided by RefSeq, Jul 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ACRBP; Acrosin-binding protein; Acrosin-binding protein, 60 kDa form; Cancer/testis antigen 23; Cancer/testis antigen OY-TES-1; CT23; proacrosin binding protein sp32; Proacrosin-binding protein sp32; testicular tissue protein Li 10
基因别名: ACRBP; CT23; OY-TES-1; SP32
UniProt ID: (Human) Q8NEB7
Entrez Gene ID: (Human) 84519