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Highest antigen sequence indentity to the following orthologs: Mouse (69%), Rat (69%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52230. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm. It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways. AKAP4 has also been postulated to be a potential biomarker for breast cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A kinase (PRKA) anchor protein 4; A-kinase anchor protein 4; A-kinase anchor protein 82 kDa; AKAP 82; AKAP-4; AKAP4; cancer/testis antigen 99; HI; Major sperm fibrous sheath protein; PRKA4; protein kinase A anchoring protein 4; Protein kinase A-anchoring protein 4; testis-specific gene HI
基因别名: AKAP 82; AKAP-4; AKAP4; AKAP82; CT99; FSC1; hAKAP82; HI; p82; PRKA4
UniProt ID: (Human) Q5JQC9
Entrez Gene ID: (Human) 8852