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产品信息
RP-75637
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
Amino acids Gly311- Ser426 containing an N-terminal His-tag
标签
His-tag
分类
Recombinant
类型
Protein
纯度
>95%, by SDS-PAGE under reducing conditions
偶联物
形式
Liquid
浓度
0.153 mg/mL
纯化类型
purified
保存液
tris HCl, pH 8, with 1mM EDTA, 50% glycerol
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
RP-75637 contains purified recombinant human Inhibin beta A protein with an N-terminal hexahistidine tag.
RP-75637 may be used as a positive control in many immunological assays.
靶标信息
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activin beta-A chain; EDF; erythroid differentiation factor; Erythroid differentiation protein; follicle-stimulating hormone-releasing protein; FSH-releasing protein; Inhibin beta A chain; inhibin, beta A (activin A, activin AB alpha polypeptide); Inhibin, beta-1
基因别名: EDF; FRP; INHBA
UniProt ID: (Human) P08476
Entrez Gene ID: (Human) 3624
