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产品信息
RP-108384
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
YVLPVKLEMEMVIQQYEKAKVIQDEQLERLTQICQEQGFEIRQLRAHLAQQDLDLAAEREAALQAPHVLSQPRSRFKVLE
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
1M urea/PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83967. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
C15orf27 is a voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum. Despite the presence of a voltage-sensor segment, it does not form a functional ion channel and its precise role remains unclear. The protein undergoes both rapid and slow structural rearrangements in response to changes in voltage, and contains a zinc-binding site that can regulate the slow conformational transition.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HsHVRP1; hTMEM266; Hv1 related protein 1; HV1-related protein 1; Transmembrane protein 266; transmembrane protein C15orf27
基因别名: C15orf27; HVRP1; TMEM266
UniProt ID: (Human) Q2M3C6
Entrez Gene ID: (Human) 123591
