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产品信息
PHC1264
应用
建议稀释比
已发表文章
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
Human CCL17 recombinant protein contains 71 amino acids
分子量
8 kDa
分类
Recombinant
类型
Protein
纯度
>98% by SDS-PAGE
内毒素浓度
<0.1 ng/µg
活性
ED50 = 1 - 10 ng/mL; determined by the dose-dependent chemotaxis of human T-cells.
偶联物
形式
Lyophilized
纯化类型
purified
内含物
no preservative
保存条件
-20°C
运输条件
Wet ice (domestic); Wet or Dry ice (international)
产品详细信息
Carrier-Free
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute this lyophilized preparation with sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in tissue culture grade buffered solutions with heat inactivated fetal calf serum or low endotoxin BSA.
Storage: This lyophilized preparation is stable at 2°C to 8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2°C to 8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeated freeze/thaw cycles.
靶标信息
TARC ligand (CCL17) belongs to the CC chemokine family. It is a small cytokine and the gene is located on q arm of chromosome 16, in humans, along with other chemokines. TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8. It plays an important role in T cell development in thymus as well as in trafficking and activation of mature T cells.
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生物信息学
蛋白别名: C-C motif chemokine; C-C motif chemokine 17; CC chemokine TARC; chemokine (C-C motif) ligand 17; small inducible cytokine subfamily A (Cys-Cys), member 17; Small-inducible cytokine A17; T cell-directed CC chemokine; Thymus and activation-regulated chemokine
基因别名: A-152E5.3; ABCD-2; CCL17; SCYA17; TARC
UniProt ID: (Human) Q92583
Entrez Gene ID: (Human) 6361
